HIT-result

Type	Detail
Target ID	T85Y6T
Protein Name	Adenylate cyclase type 8
Uniprot ID	P40145
Protein Name Alias	EC 4.6.1.1; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca(2+)/calmodulin-activated adenylyl cyclase
Gene ID	114
Gene Symbol	ADCY8
Gene Alias	NA
TTD	NA
Pfam	PF00211 ; PF16214 ; PF06327
GO	0034199:activation of protein kinase A activity 0051721:protein phosphatase 2A binding 0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway 0071315:cellular response to morphine 0003091:renal water homeostasis 0008294:calcium- and calmodulin-responsive adenylate cyclase activity 0005524:ATP binding 0046983:protein dimerization activity 0007626:locomotory behavior 0030425:dendrite 0002862:negative regulation of inflammatory response to antigenic stimulus 0007204:positive regulation of cytosolic calcium ion concentration 0080135:regulation of cellular response to stress 0016020:membrane 0007193:adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 0032809:neuronal cell body membrane 0030665:clathrin-coated vesicle membrane 0048786:presynaptic active zone 0007186:G protein-coupled receptor signaling pathway 0060076:excitatory synapse 0046872:metal ion binding 1900273:positive regulation of long-term synaptic potentiation 0071377:cellular response to glucagon stimulus 0046982:protein heterodimerization activity 0006171:cAMP biosynthetic process 0005516:calmodulin binding 0071333:cellular response to glucose stimulus 0051260:protein homooligomerization 0098685:Schaffer collateral - CA1 synapse 0005886:plasma membrane 0042593:glucose homeostasis 0150076:neuroinflammatory response 0035774:positive regulation of insulin secretion involved in cellular response to glucose stimulus 0098978:glutamatergic synapse 0005887:integral component of plasma membrane 0007611:learning or memory 0051259:protein complex oligomerization 0038003:opioid receptor signaling pathway 0007616:long-term memory 0004016:adenylate cyclase activity 0051480:regulation of cytosolic calcium ion concentration 0007613:memory 0042803:protein homodimerization activity 0016323:basolateral plasma membrane 0071277:cellular response to calcium ion 1904322:cellular response to forskolin 0031915:positive regulation of synaptic plasticity 0044853:plasma membrane raft 0032793:positive regulation of CREB transcription factor activity 0005905:clathrin-coated pit 0005901:caveola 0045121:membrane raft 0099056:integral component of presynaptic membrane 0003779:actin binding 0010255:glucose mediated signaling pathway 0014069:postsynaptic density 0007190:activation of adenylate cyclase activity 0030424:axon 0007165:signal transduction 0098686:hippocampal mossy fiber to CA3 synapse 1900454:positive regulation of long-term synaptic depression 0016324:apical plasma membrane
PDB	NA
Drugbank	NA
KEGG	hsa:114

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Name: Morphine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum