Compound Description
| ID: C0128 | Common name: Hydrastine |
| IUPAC: (3S)-6,7-dimethoxy-3-[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one | CAS: CAS:118-08-1 |
| Chembl ID: CHEMBL1256919 | Pubchem ID: CID:197835 |
| Formula: C21H21NO6 | TCM-ID: TCMC1337 |
| Smiles: COc1c(OC)ccc2c1C(=O)O[C@@H]2[C@@H]1N(C)CCc2c1cc1OCOc1c2 | |
| Alias:
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-;
Hydrastine; (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone; 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.; (-)-Hydrastine; (-)-β-Hydrastine; (1R,9S)-β-Hydrastine; l-Hydrastine; β-Hydrastine |
Structure:
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Related Targets (Total: 1)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T85C8T | Serine/threonine-protein kinase PAK 4 | PAK4 |
O96013 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 9)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0760 | Yu Huang Lian | 萸黄连 | Coptis deltoidea | Coptis chinensis |
| H1243 | Huang Lian Xu | 黄连须 | Coptis deltoidea | Coptis chinensis |
| H0682 | Xiong Huang Lian | 雄黄连 | Coptis deltoidea | Coptis chinensis |
| H1242 | Huang Lian Gan Jin Gao | 黄连干浸膏 | Coptis deltoidea | Coptis chinensis |
| H1241 | Huang Lian | 黄连 | Coptis deltoidea | Coptis chinensis |
| H0785 | Ze Xi Huang Lian | 择细黄连 | Coptis deltoidea | Coptis chinensis |
| H0029 | Jiang Huang Lian | 姜黄连 | Coptis deltoidea | Coptis chinensis |
| H0082 | Jiu Huang Lian | 酒黄连 | Coptis deltoidea | Coptis chinensis |
| H0872 | Chuan Huang Lian | 川黄连 | rhizome of chinese goldthread | Coptis chinensis |
Ckey description of the interaction between compound and target