Compound Description
| ID: C0308 | Common name: Piceatannol |
| IUPAC: 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol | CAS: CAS:10083-24-6 |
| Chembl ID: CHEMBL69863 | Pubchem ID: CID:667639 |
| Formula: C14H12O4 | TCM-ID: TCMC1892 |
| Smiles: Oc1cc(/C=C/c2ccc(c(c2)O)O)cc(c1)O | |
| Alias:
1,2-Benzenediol, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-;
3,3',4,5'-Stilbenetetrol, (E)-; Piceatannol; 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol; (E)-Piceatannol; Astringenin; trans-3,3',4,5'-Tetrahydroxystilbene; trans-Piceatannol |
Structure:
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Related Targets (Total: 10)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T69XEM | Tyrosine-protein kinase SYK | SYK |
P43405 |
A | 6 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
A | 2 Reference(s) |
| T52VL6 | Signal transducer and activator of transcription 5A | STAT5A |
P42229 |
A | 1 Reference(s) |
| T22J9V | Tyrosine-protein kinase JAK1 | JAK1 |
P23458 |
A | 1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
A | 1 Reference(s) |
| T28WZ9 | Ribosyldihydronicotinamide dehydrogenase [quinone] | NQO2 |
P16083 |
B | 1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
B | 1 Reference(s) |
| T42GML | NA | MIR183 |
NA |
C | 1 Reference(s) |
| T95H9O | Stromelysin-2 | MMP10 |
P09238 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 13)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
| H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
| H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
Ckey description of the interaction between compound and target