HIT-result

Target Description

Type	Detail
Target ID	T28WZ9
Protein Name	Ribosyldihydronicotinamide dehydrogenase [quinone]
Uniprot ID	P16083
Protein Name Alias	EC 1.10.5.1
Gene ID	4835
Gene Symbol	NQO2
Gene Alias	NMOR2
TTD	T75498: Successful target
Pfam	PF02525
GO	0070062:extracellular exosome 2000379:positive regulation of reactive oxygen species metabolic process 0006805:xenobiotic metabolic process 0001512:dihydronicotinamide riboside quinone reductase activity 0003955:NAD(P)H dehydrogenase (quinone) activity 0005829:cytosol 1904707:positive regulation of vascular associated smooth muscle cell proliferation 0016661:oxidoreductase activity, acting on other nitrogenous compounds as donors 1905594:resveratrol binding 0009055:electron transfer activity 0005654:nucleoplasm 1901662:quinone catabolic process 0008270:zinc ion binding 0043525:positive regulation of neuron apoptotic process 0007613:memory 0016491:oxidoreductase activity 0042803:protein homodimerization activity 0071949:FAD binding 0070374:positive regulation of ERK1 and ERK2 cascade 0031404:chloride ion binding 1904408:melatonin binding
PDB	3G5M ; 3NFR ; 2BZS ; 3NHW ; 1QR2 ; 3FW1 ; 3OX3 ; 3OVM ; 3TE7 ; 5LBW ; 2QR2 ; 2QWX ; 3OX1 ; 2QMY ; 3O73 ; 2QX8 ; 4QOH ; 3NHP ; 5LBZ ; 5LBT ; 2QX9 ; 3OWX ; 3O2N ; 3UXH ; 1XI2 ; 4QOF ; 3TZB ; 4ZVM ; 3NHK ; 3OX2 ; 4U7F ; 3TEM ; 4ZVK ; 1ZX1 ; 4U7G ; 3OWH ; 3NHJ ; 4XDG ; 4ZVL ; 3UXE ; 4GR9 ; 3NHF ; 2QX6 ; 3NHS ; 4FGK ; 4QOD ; 3NHR ; 2QX4 ; 3NHU ; 4QOG ; 4XDH ; 4GQI ; 4QOI ; 5BUC ; 3GAM ; 3NHL ; 4U7H ; 4QOE ; 5LBY ; 2QMZ ; 4FGL ; 5LBU ; 4FGJ ; 1SG0 ; 4ZVN ; 3NHY ; 4QOJ
Drugbank	DB08744 ; DB01065 ; DB04216 ; DB02709 ; DB03541 ; DB00157 ; DB08228 ; DB06695 ; DB00170 ; DB01087 ; DB08190 ; DB03147 ; DB07339 ; DB04253
KEGG	hsa:4835

Type

Detail

Target ID

T28WZ9

Protein Name

Ribosyldihydronicotinamide dehydrogenase [quinone]

Uniprot ID

P16083

Protein Name Alias

EC 1.10.5.1

Gene ID

4835

Gene Symbol

NQO2

Gene Alias

NMOR2

TTD

T75498: Successful target

Pfam

PF02525

0070062:extracellular exosome

2000379:positive regulation of reactive oxygen species metabolic process

0006805:xenobiotic metabolic process

0001512:dihydronicotinamide riboside quinone reductase activity

0003955:NAD(P)H dehydrogenase (quinone) activity

0005829:cytosol

1904707:positive regulation of vascular associated smooth muscle cell proliferation

0016661:oxidoreductase activity, acting on other nitrogenous compounds as donors

1905594:resveratrol binding

0009055:electron transfer activity

0005654:nucleoplasm

1901662:quinone catabolic process

0008270:zinc ion binding

0043525:positive regulation of neuron apoptotic process

0007613:memory

0016491:oxidoreductase activity

0042803:protein homodimerization activity

0071949:FAD binding

0070374:positive regulation of ERK1 and ERK2 cascade

0031404:chloride ion binding

1904408:melatonin binding

PDB

3G5M ; 3NFR ; 2BZS ; 3NHW ; 1QR2 ; 3FW1 ; 3OX3 ; 3OVM ; 3TE7 ; 5LBW ; 2QR2 ; 2QWX ; 3OX1 ; 2QMY ; 3O73 ; 2QX8 ; 4QOH ; 3NHP ; 5LBZ ; 5LBT ; 2QX9 ; 3OWX ; 3O2N ; 3UXH ; 1XI2 ; 4QOF ; 3TZB ; 4ZVM ; 3NHK ; 3OX2 ; 4U7F ; 3TEM ; 4ZVK ; 1ZX1 ; 4U7G ; 3OWH ; 3NHJ ; 4XDG ; 4ZVL ; 3UXE ; 4GR9 ; 3NHF ; 2QX6 ; 3NHS ; 4FGK ; 4QOD ; 3NHR ; 2QX4 ; 3NHU ; 4QOG ; 4XDH ; 4GQI ; 4QOI ; 5BUC ; 3GAM ; 3NHL ; 4U7H ; 4QOE ; 5LBY ; 2QMZ ; 4FGL ; 5LBU ; 4FGJ ; 1SG0 ; 4ZVN ; 3NHY ; 4QOJ

Drugbank

DB08744 ; DB01065 ; DB04216 ; DB02709 ; DB03541 ; DB00157 ; DB08228 ; DB06695 ; DB00170 ; DB01087 ; DB08190 ; DB03147 ; DB07339 ; DB04253

KEGG

hsa:4835

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0013	Ji Shi Teng	鸡矢藤	Fevervine	Paederia scandens
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H0416	Shan Shen	山参	NA	Panax ginseng
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 26)