Compound Description
| ID: C0920 | Common name: Arecoline |
| IUPAC: methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate | CAS: CAS:63-75-2 |
| Chembl ID: CHEMBL7303 | Pubchem ID: CID:2230 |
| Formula: C8H13NO2 | TCM-ID: TCMC719 |
| Smiles: COC(=O)C1=CCCN(C1)C | |
| Alias:
Arecoline;
Nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester; 1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester; 3-Methoxycarbonyl-1-methyl-1,2,5,6-tetrahydropyridine; Arecaidine methyl ester; Arecolin; Arecoline base; Methyl 1,2,5,6-tetrahydro-1-methylnicotinate; Methyl N-methyl-1,2,5,6-tetrahydronicotinate; Methyl arecaidin; Methylarecaidine; NSC 56321 |
Structure:
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Related Targets (Total: 16)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T06MQM | Heat shock protein beta-1 | HSPB1 |
P04792 |
A | 1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
A | 1 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
B | 1 Reference(s) |
| T61SU2 | Coxsackievirus and adenovirus receptor | CXADR |
P78310 |
C | 1 Reference(s) |
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
C | 1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
C | 1 Reference(s) |
| T99XJ1 | Serpin H1 | SERPINH1 |
P50454 |
C | 1 Reference(s) |
| T18C4B | Methylated-DNA--protein-cysteine methyltransferase | MGMT |
P16455 |
C | 1 Reference(s) |
| T19F7P | Proteinase-activated receptor 1 | F2R |
P25116 |
C | 1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
C | 1 Reference(s) |
| T91T8I | Glucose-6-phosphatase catalytic subunit 1 | G6PC1 |
P35575 |
C | 1 Reference(s) |
| T68R23 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | PCK2 |
Q16822 |
C | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
C | 1 Reference(s) |
| T18DUA | Tight junction protein ZO-1 | TJP1 |
Q07157 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 4)
Ckey description of the interaction between compound and target