HIT-result

Type	Detail
Target ID	T02HVB
Protein Name	Midkine
Uniprot ID	P21741
Protein Name Alias	MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein
Gene ID	4192
Gene Symbol	MDK
Gene Alias	MK1; NEGF2
TTD	T03878: Research target
Pfam	PF05196 ; PF01091
GO	1905555:positive regulation of blood vessel branching 0002232:leukocyte chemotaxis involved in inflammatory response 0045590:negative regulation of regulatory T cell differentiation 1904036:negative regulation of epithelial cell apoptotic process 0045785:positive regulation of cell adhesion 0007010:cytoskeleton organization 0042246:tissue regeneration 0045582:positive regulation of T cell differentiation 0050729:positive regulation of inflammatory response 0035374:chondroitin sulfate binding 2000179:positive regulation of neural precursor cell proliferation 0010976:positive regulation of neuron projection development 0048714:positive regulation of oligodendrocyte differentiation 0051781:positive regulation of cell division 1905653:positive regulation of artery morphogenesis 0061036:positive regulation of cartilage development 1904996:positive regulation of leukocyte adhesion to vascular endothelial cell 0007399:nervous system development 0008083:growth factor activity 0009611:response to wounding 0043524:negative regulation of neuron apoptotic process 0048477:oogenesis 0010718:positive regulation of epithelial to mesenchymal transition 0010759:positive regulation of macrophage chemotaxis 0030154:cell differentiation 0071673:positive regulation of smooth muscle cell chemotaxis 1900026:positive regulation of substrate adhesion-dependent cell spreading 2000391:positive regulation of neutrophil extravasation 0106015:negative regulation of inflammatory response to wounding 0044849:estrous cycle 0007165:signal transduction 0005576:extracellular region 0090090:negative regulation of canonical Wnt signaling pathway 2000249:regulation of actin cytoskeleton reorganization 0030335:positive regulation of cell migration 0032735:positive regulation of interleukin-12 production 0002286:T cell activation involved in immune response 1904399:heparan sulfate binding 0106091:glial cell projection elongation 2000347:positive regulation of hepatocyte proliferation 1905564:positive regulation of vascular endothelial cell proliferation 0106016:positive regulation of inflammatory response to wounding 0010838:positive regulation of keratinocyte proliferation 0032330:regulation of chondrocyte differentiation 1903039:positive regulation of leukocyte cell-cell adhesion 0030279:negative regulation of ossification 0007219:Notch signaling pathway 0010996:response to auditory stimulus 0002690:positive regulation of leukocyte chemotaxis 0046850:regulation of bone remodeling 0007162:negative regulation of cell adhesion 2001224:positive regulation of neuron migration 0008201:heparin binding 0090023:positive regulation of neutrophil chemotaxis 0010667:negative regulation of cardiac muscle cell apoptotic process 0030325:adrenal gland development
PDB	1MKN ; 1MKC
Drugbank	NA
KEGG	hsa:4192

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Name: Morphine

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Name: yohimbine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum