HIT-result

Target Description

Type	Detail
Target ID	T02XPT
Protein Name	SPARC
Uniprot ID	P09486
Protein Name Alias	Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine
Gene ID	6678
Gene Symbol	SPARC
Gene Alias	ON
TTD	T09439: Research target
Pfam	PF09289 ; PF00050 ; PF10591
GO	0051592:response to calcium ion 0005576:extracellular region 0031092:platelet alpha granule membrane 0002576:platelet degranulation 0045471:response to ethanol 0046686:response to cadmium ion 0098978:glutamatergic synapse 0050840:extracellular matrix binding 0043231:intracellular membrane-bounded organelle 0005604:basement membrane 0009629:response to gravity 0048856:anatomical structure development 0005886:plasma membrane 0022604:regulation of cell morphogenesis 0033591:response to L-ascorbic acid 0043434:response to peptide hormone 0016363:nuclear matrix 0005509:calcium ion binding 0001503:ossification 0034097:response to cytokine 0010288:response to lead ion 0007507:heart development 0031091:platelet alpha granule 0005518:collagen binding 0031093:platelet alpha granule lumen 0051591:response to cAMP 0071682:endocytic vesicle lumen 0042060:wound healing 0062023:collagen-containing extracellular matrix 0009986:cell surface 0030198:extracellular matrix organization 0051384:response to glucocorticoid 0005615:extracellular space 0005737:cytoplasm 0016525:negative regulation of angiogenesis 0032496:response to lipopolysaccharide 0048839:inner ear development 0030324:lung development 0001937:negative regulation of endothelial cell proliferation 0010595:positive regulation of endothelial cell migration 0050807:regulation of synapse organization 0006898:receptor-mediated endocytosis
PDB	1SRA ; 1BMO ; 1NUB ; 2V53
Drugbank	DB14481 ; DB11348 ; DB11093
KEGG	hsa:6678

Type

Detail

Target ID

T02XPT

Protein Name

SPARC

Uniprot ID

P09486

Protein Name Alias

Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine

Gene ID

6678

Gene Symbol

SPARC

Gene Alias

TTD

T09439: Research target

Pfam

PF09289 ; PF00050 ; PF10591

0051592:response to calcium ion

0005576:extracellular region

0031092:platelet alpha granule membrane

0002576:platelet degranulation

0045471:response to ethanol

0046686:response to cadmium ion

0098978:glutamatergic synapse

0050840:extracellular matrix binding

0043231:intracellular membrane-bounded organelle

0005604:basement membrane

0009629:response to gravity

0048856:anatomical structure development

0005886:plasma membrane

0022604:regulation of cell morphogenesis

0033591:response to L-ascorbic acid

0043434:response to peptide hormone

0016363:nuclear matrix

0005509:calcium ion binding

0001503:ossification

0034097:response to cytokine

0010288:response to lead ion

0007507:heart development

0031091:platelet alpha granule

0005518:collagen binding

0031093:platelet alpha granule lumen

0051591:response to cAMP

0071682:endocytic vesicle lumen

0042060:wound healing

0062023:collagen-containing extracellular matrix

0009986:cell surface

0030198:extracellular matrix organization

0051384:response to glucocorticoid

0005615:extracellular space

0005737:cytoplasm

0016525:negative regulation of angiogenesis

0032496:response to lipopolysaccharide

0048839:inner ear development

0030324:lung development

0001937:negative regulation of endothelial cell proliferation

0010595:positive regulation of endothelial cell migration

0050807:regulation of synapse organization

0006898:receptor-mediated endocytosis

PDB

1SRA ; 1BMO ; 1NUB ; 2V53

Drugbank

DB14481 ; DB11348 ; DB11093

KEGG

hsa:6678

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0416	Shan Shen	山参	NA	Panax ginseng
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0339	Qing Dai	青黛	Natural indigo	Indigo naturalis
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0357	Ren Shen	人参	Ginseng	Panax ginseng

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 32)