Target Description

Type Detail
Target ID T28V82
Protein Name Wilms tumor protein
Uniprot ID P19544
Protein Name Alias WT33
Gene ID 7490
Gene Symbol WT1
Gene Alias NA
TTD T29960: Clinical Trial target
Pfam PF02165 ; PF00096
0006355:regulation of transcription, DNA-templated

0072112:glomerular visceral epithelial cell differentiation

2000020:positive regulation of male gonad development

0000976:transcription regulatory region sequence-specific DNA binding

0060923:cardiac muscle cell fate commitment

0072284:metanephric S-shaped body morphogenesis

0007530:sex determination

0043066:negative regulation of apoptotic process


0007507:heart development

0061032:visceral serous pericardium development

0044729:hemi-methylated DNA-binding

0072075:metanephric mesenchyme development

0010385:double-stranded methylated DNA binding

0060539:diaphragm development


0001657:ureteric bud development

2000195:negative regulation of female gonad development

0043065:positive regulation of apoptotic process

0030308:negative regulation of cell growth

0060231:mesenchymal to epithelial transition

2001076:positive regulation of metanephric ureteric bud development

0007281:germ cell development


0001228:DNA-binding transcription activator activity, RNA polymerase II-specific


0001658:branching involved in ureteric bud morphogenesis

0071320:cellular response to cAMP

1902895:positive regulation of pri-miRNA transcription by RNA polymerase II


0043565:sequence-specific DNA binding

0001822:kidney development

0070742:C2H2 zinc finger domain binding

0035802:adrenal cortex formation

0030855:epithelial cell differentiation

0045893:positive regulation of transcription, DNA-templated

0008270:zinc ion binding

0003723:RNA binding

0003700:DNA-binding transcription factor activity

0045944:positive regulation of transcription by RNA polymerase II

0016607:nuclear speck

0071371:cellular response to gonadotropin stimulus

0009888:tissue development


0007356:thorax and anterior abdomen determination

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0008584:male gonad development

0032835:glomerulus development

0072302:negative regulation of metanephric glomerular mesangial cell proliferation

0072207:metanephric epithelium development

0010628:positive regulation of gene expression

0060421:positive regulation of heart growth

0017148:negative regulation of translation

0045892:negative regulation of transcription, DNA-templated

0030325:adrenal gland development

0008406:gonad development

0008380:RNA splicing

0003156:regulation of animal organ formation

1905643:positive regulation of DNA methylation

0032836:glomerular basement membrane development

0000122:negative regulation of transcription by RNA polymerase II

0008285:negative regulation of cell population proliferation

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0072166:posterior mesonephric tubule development

0043010:camera-type eye development

0030539:male genitalia development

0006357:regulation of transcription by RNA polymerase II

PDB 2JP9 ; 5KL6 ; 6BLW ; 1LU6 ; 4R2R ; 5KL4 ; 1XF7 ; 2G7W ; 4R2P ; 2JPA ; 5KL2 ; 5KL5 ; 4R2S ; 2G7X ; 6RSY ; 2G7T ; 4R2Q ; 4R2E ; 4WUU ; 6B0O ; 6B0R ; 2G7V ; 6B0P ; 2PRT ; 6B0Q ; 5KL3 ; 3MYJ ; 5KL7 ; 3HPJ
Drugbank NA
KEGG hsa:7490

Related Compounds  (Total: 3)

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Name: Progesterone
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Name: Fructose
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Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione

Related Herbs  (Total: 15)

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H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0357 Ren Shen人参 GinsengPanax ginseng
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum