HIT-result

Type	Detail
Target ID	T33VZN
Protein Name	Retinoic acid receptor beta
Uniprot ID	P10826
Protein Name Alias	RAR-beta; HBV-activated protein; Nuclear receptor subfamily 1 group B member 2; RAR-epsilon
Gene ID	5915
Gene Symbol	RARB
Gene Alias	HAP; NR1B2
TTD	T61657: Successful target
Pfam	PF00105 ; PF00104
GO	0021756:striatum development 0003417:growth plate cartilage development 1990837:sequence-specific double-stranded DNA binding 0043066:negative regulation of apoptotic process 0022008:neurogenesis 0045666:positive regulation of neuron differentiation 0032331:negative regulation of chondrocyte differentiation 0009755:hormone-mediated signaling pathway 0008285:negative regulation of cell population proliferation 0046965:retinoid X receptor binding 0002068:glandular epithelial cell development 0001657:ureteric bud development 0043065:positive regulation of apoptotic process 0004879:nuclear receptor activity 0044877:protein-containing complex binding 0030154:cell differentiation 0035264:multicellular organism growth 0005654:nucleoplasm 0031641:regulation of myelination 0055012:ventricular cardiac muscle cell differentiation 0048048:embryonic eye morphogenesis 0003677:DNA binding 0005737:cytoplasm 0008270:zinc ion binding 0000785:chromatin 0045944:positive regulation of transcription by RNA polymerase II 0008144:drug binding 0005634:nucleus 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0035116:embryonic hindlimb morphogenesis 0006367:transcription initiation from RNA polymerase II promoter 0003148:outflow tract septum morphogenesis 0048384:retinoic acid receptor signaling pathway 0007165:signal transduction 0000122:negative regulation of transcription by RNA polymerase II 0048566:embryonic digestive tract development 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific
PDB	6SSQ ; 4JYI ; 4DM6 ; 1HRA ; 1XAP ; 4JYH ; 5UAN ; 4DM8 ; 4JYG
Drugbank	DB02877 ; DB00799 ; DB04942 ; DB00523 ; DB05785 ; DB00755 ; DB12808 ; DB00210 ; DB00459 ; DB00926
KEGG	hsa:5915

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Name: Tretinoin

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Name: Acetaldehyde

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Name: Curcumin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0289	Niu Bang Zi	牛蒡子	Great burdock fruit	Arctium lappa
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0077	Jiu	酒	Ethanol	Vinum
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens