HIT-result

Type	Detail
Target ID	T34E5V
Protein Name	Endothelin-1 receptor
Uniprot ID	P25101
Protein Name Alias	Endothelin receptor type A; ET-A; ETA-R; hET-AR
Gene ID	1909
Gene Symbol	EDNRA
Gene Alias	ETA; ETRA
TTD	T23499: Successful target
Pfam	PF00001
GO	0014824:artery smooth muscle contraction 0008217:regulation of blood pressure 0007585:respiratory gaseous exchange by respiratory system 0060322:head development 0007193:adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 0004962:endothelin receptor activity 0004435:phosphatidylinositol phospholipase C activity 0007204:positive regulation of cytosolic calcium ion concentration 0006939:smooth muscle contraction 0042310:vasoconstriction 0048484:enteric nervous system development 0007507:heart development 0001569:branching involved in blood vessel morphogenesis 0007165:signal transduction 0007190:activation of adenylate cyclase activity 0001666:response to hypoxia 0001701:in utero embryonic development 0007202:activation of phospholipase C activity 0014032:neural crest cell development 0010827:regulation of glucose transmembrane transport 0008283:cell population proliferation 0005886:plasma membrane 0007186:G protein-coupled receptor signaling pathway 0005887:integral component of plasma membrane
PDB	NA
Drugbank	DB05290 ; DB06460 ; DB06268 ; DB00559 ; DB04883 ; DB00945 ; DB06199 ; DB06677 ; DB06403 ; DB12548 ; DB06558 ; DB05367 ; DB04674 ; DB08932
KEGG	hsa:1909

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0323	Qian Hu	前胡	Common hogfennel	Angelica decursiva
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0461	Shi Jun Zi Ren	使君子仁	NA	Combretum indicum

Target Description