HIT-result

Type	Detail
Target ID	T45TMC
Protein Name	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Uniprot ID	P19174
Protein Name Alias	EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1
Gene ID	5335
Gene Symbol	PLCG1
Gene Alias	PLC1
TTD	T93922: Research target
Pfam	PF00018 ; PF00168 ; PF00387 ; PF00388 ; PF00017
GO	0004435:phosphatidylinositol phospholipase C activity 0030027:lamellipodium 0002862:negative regulation of inflammatory response to antigenic stimulus 0005911:cell-cell junction 0038095:Fc-epsilon receptor signaling pathway 0001701:in utero embryonic development 0050852:T cell receptor signaling pathway 0071364:cellular response to epidermal growth factor stimulus 0098978:glutamatergic synapse 0035254:glutamate receptor binding 0019722:calcium-mediated signaling 0050804:modulation of chemical synaptic transmission 0098685:Schaffer collateral - CA1 synapse 0007202:activation of phospholipase C activity 0050900:leukocyte migration 0005886:plasma membrane 0016032:viral process 0005829:cytosol 0009395:phospholipid catabolic process 0007411:axon guidance 0007173:epidermal growth factor receptor signaling pathway 0005168:neurotrophin TRKA receptor binding 0008180:COP9 signalosome 0005509:calcium ion binding 1905564:positive regulation of vascular endothelial cell proliferation 0007165:signal transduction 2000353:positive regulation of endothelial cell apoptotic process 0016477:cell migration 0010634:positive regulation of epithelial cell migration 0046488:phosphatidylinositol metabolic process 0050429:calcium-dependent phospholipase C activity 0051281:positive regulation of release of sequestered calcium ion into cytosol 0043647:inositol phosphate metabolic process 0005737:cytoplasm 0001726:ruffle 0045766:positive regulation of angiogenesis 0043536:positive regulation of blood vessel endothelial cell migration 0010863:positive regulation of phospholipase C activity 0030971:receptor tyrosine kinase binding 0019901:protein kinase binding 0038096:Fc-gamma receptor signaling pathway involved in phagocytosis 0042995:cell projection
PDB	4FBN ; 4EY0 ; 2HSP ; 1HSQ
Drugbank	NA
KEGG	hsa:5335

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Name: heparin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum