Target Description

Type Detail
Target ID T47OCS
Protein Name Fibroblast growth factor 10
Uniprot ID O15520
Protein Name Alias FGF-10;  Keratinocyte growth factor 2
Gene ID 2255
Gene Symbol FGF10
Gene Alias NA
TTD T62763: Discontinued target
Pfam PF00167
GO
2001240:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

0046579:positive regulation of Ras protein signal transduction

0050731:positive regulation of peptidyl-tyrosine phosphorylation

0070371:ERK1 and ERK2 cascade

0061033:secretion by lung epithelial cell involved in lung growth

0046877:regulation of saliva secretion

0031016:pancreas development

0070352:positive regulation of white fat cell proliferation

0031069:hair follicle morphogenesis

0001525:angiogenesis

0048536:spleen development

0070384:Harderian gland development

0005576:extracellular region

1900087:positive regulation of G1/S transition of mitotic cell cycle

0010838:positive regulation of keratinocyte proliferation

0032925:regulation of activin receptor signaling pathway

0060595:fibroblast growth factor receptor signaling pathway involved in mammary gland specification

0048538:thymus development

0060436:bronchiole morphogenesis

0032355:response to estradiol

0060667:branch elongation involved in salivary gland morphogenesis

0060661:submandibular salivary gland formation

0021983:pituitary gland development

0048754:branching morphogenesis of an epithelial tube

0010634:positive regulation of epithelial cell migration

0007431:salivary gland development

0035019:somatic stem cell population maintenance

0042060:wound healing

0000187:activation of MAPK activity

0060915:mesenchymal cell differentiation involved in lung development

0042056:chemoattractant activity

0045596:negative regulation of cell differentiation

0043410:positive regulation of MAPK cascade

0045747:positive regulation of Notch signaling pathway

0050679:positive regulation of epithelial cell proliferation

0008589:regulation of smoothened signaling pathway

0031076:embryonic camera-type eye development

0045739:positive regulation of DNA repair

0009986:cell surface

0060664:epithelial cell proliferation involved in salivary gland morphogenesis

0030154:cell differentiation

0008083:growth factor activity

0060174:limb bud formation

0070075:tear secretion

0060665:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

0034394:protein localization to cell surface

0051145:smooth muscle cell differentiation

0042475:odontogenesis of dentin-containing tooth

0060428:lung epithelium development

0060496:mesenchymal-epithelial cell signaling involved in lung development

0030916:otic vesicle formation

0001759:organ induction

0042246:tissue regeneration

0060447:bud outgrowth involved in lung branching

0008284:positive regulation of cell population proliferation

0060879:semicircular canal fusion

0005111:type 2 fibroblast growth factor receptor binding

0060173:limb development

0051897:positive regulation of protein kinase B signaling

0090263:positive regulation of canonical Wnt signaling pathway

0042693:muscle cell fate commitment

0007368:determination of left/right symmetry

0032808:lacrimal gland development

0050671:positive regulation of lymphocyte proliferation

0000165:MAPK cascade

0050930:induction of positive chemotaxis

0048146:positive regulation of fibroblast proliferation

0009880:embryonic pattern specification

0032496:response to lipopolysaccharide

0032781:positive regulation of ATPase activity

0060510:type II pneumocyte differentiation

0001823:mesonephros development

0001934:positive regulation of protein phosphorylation

0048807:female genitalia morphogenesis

0050677:positive regulation of urothelial cell proliferation

0005886:plasma membrane

0050918:positive chemotaxis

0060019:radial glial cell differentiation

0030878:thyroid gland development

0061115:lung proximal/distal axis specification

0001656:metanephros development

0045944:positive regulation of transcription by RNA polymerase II

0005634:nucleus

0010628:positive regulation of gene expression

0008543:fibroblast growth factor receptor signaling pathway

0030334:regulation of cell migration

0060054:positive regulation of epithelial cell proliferation involved in wound healing

0030538:embryonic genitalia morphogenesis

0008285:negative regulation of cell population proliferation

0008201:heparin binding

0071157:negative regulation of cell cycle arrest

0050673:epithelial cell proliferation

0005615:extracellular space

0003338:metanephros morphogenesis

0060449:bud elongation involved in lung branching

0031532:actin cytoskeleton reorganization

0001974:blood vessel remodeling

0051549:positive regulation of keratinocyte migration

0005104:fibroblast growth factor receptor binding

0048557:embryonic digestive tract morphogenesis

0060615:mammary gland bud formation

0060513:prostatic bud formation

0005737:cytoplasm

0048808:male genitalia morphogenesis

0050872:white fat cell differentiation

0000132:establishment of mitotic spindle orientation

0070374:positive regulation of ERK1 and ERK2 cascade

0009887:animal organ morphogenesis

0050674:urothelial cell proliferation

0060430:lung saccule development

0071338:positive regulation of hair follicle cell proliferation

0030949:positive regulation of vascular endothelial growth factor receptor signaling pathway

PDB 1NUN
Drugbank NA
KEGG hsa:2255

Related Compounds  (Total: 2)

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C0055
Name: Estradiol
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C1113
Name: heparin


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