Target Description

Type Detail
Target ID T50E9D
Protein Name Metallothionein-3
Uniprot ID P25713
Protein Name Alias MT-3;  GIFB;  GIF;  Growth inhibitory factor;  Metallothionein-III;  MT-III
Gene ID 4504
Gene Symbol MT3
Gene Alias NA
TTD NA
Pfam PF00131
GO
0005634:nucleus

0071280:cellular response to copper ion

0006875:cellular metal ion homeostasis

0046872:metal ion binding

0019430:removal of superoxide radicals

2000378:negative regulation of reactive oxygen species metabolic process

0005829:cytosol

0001934:positive regulation of protein phosphorylation

0060049:regulation of protein glycosylation

0030295:protein kinase activator activity

0016570:histone modification

0010507:negative regulation of autophagy

0006707:cholesterol catabolic process

0008270:zinc ion binding

0036091:positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

0006882:cellular zinc ion homeostasis

0045892:negative regulation of transcription, DNA-templated

0055073:cadmium ion homeostasis

0043524:negative regulation of neuron apoptotic process

0043066:negative regulation of apoptotic process

0010628:positive regulation of gene expression

0055069:zinc ion homeostasis

0046870:cadmium ion binding

0045893:positive regulation of transcription, DNA-templated

0071456:cellular response to hypoxia

0010977:negative regulation of neuron projection development

2000376:positive regulation of oxygen metabolic process

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0032095:regulation of response to food

0010038:response to metal ion

0001666:response to hypoxia

0070371:ERK1 and ERK2 cascade

0030517:negative regulation of axon extension

0010273:detoxification of copper ion

0060547:negative regulation of necrotic cell death

0044242:cellular lipid catabolic process

0070374:positive regulation of ERK1 and ERK2 cascade

0043085:positive regulation of catalytic activity

0016234:inclusion body

0005507:copper ion binding

2000117:negative regulation of cysteine-type endopeptidase activity

0071732:cellular response to nitric oxide

0006112:energy reserve metabolic process

0030308:negative regulation of cell growth

0014002:astrocyte development

0008021:synaptic vesicle

0030949:positive regulation of vascular endothelial growth factor receptor signaling pathway

0033210:leptin-mediated signaling pathway

0071276:cellular response to cadmium ion

0010942:positive regulation of cell death

0034599:cellular response to oxidative stress

0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0010940:positive regulation of necrotic cell death

0043491:protein kinase B signaling

0071294:cellular response to zinc ion

0097214:positive regulation of lysosomal membrane permeability

0006829:zinc ion transport

0051354:negative regulation of oxidoreductase activity

0032148:activation of protein kinase B activity

0050821:protein stabilization

0005737:cytoplasm

0016209:antioxidant activity

0048471:perinuclear region of cytoplasm

PDB 2FJ4 ; 2FJ5 ; 2F5H
Drugbank DB09130 ; DB14487 ; DB01593 ; DB14548 ; DB12965 ; DB14533
KEGG hsa:4504

Related Compounds  (Total: 1)

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C0482
Name: Vitamin E


Related Herbs  (Total: 47)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0679 Xing Ren杏仁 Apricot seedPrunus armeniaca
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H0043 Jie Zi芥子 India mustard seedBrassica juncea
H1203 Hu Ji Sheng槲寄生 Colored mistletoeViscum coloratum
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H0256 Ming Dang Shen明党参 Medicinal changiumChangium smyrnioides
H0126 Lai Fu Zi莱菔子 Garden radish seedRaphanus sativus
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0709 Chang Shan常山 Antifebrile dichroaDichroa febrifuga
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H1171 He Zi Rou诃子肉 Medicine terminaliaTerminalia chebula
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0318 Pu Tao(1)蒲桃 SyzygiumSyzygium jambos
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0297 Niu Xi牛膝 Twotooth achyranthesAchyranthes bidentata
H0967 Di Er Cao地耳草 Japanese stJohn’swortHypericum japonicum
H0982 Bai Bu Gan Gao百部干膏 Tuber stemonaStemona tuberosa
H0977 Bai Bu百部 Tuber stemonaStemona tuberosa
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H0351 Quan Shen拳参 BistortPolygonum bistorta
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0547 Cang Qing Guo藏青果 MyrobalanTerminalia chebula
H0332 Qiao Mai荞麦 Common buckwheatFagopyrum esculentum
H1183 Hong Dou红豆 Hosie ormosiaOrmosia hosiei
H0991 Bai Bu Liu Jin Gao百部流浸膏 Tuber stemonaStemona tuberosa
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0987 Bai Bu Jin Gao百部浸膏 Tuber stemonaStemona tuberosa
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0962 Dao Dou刀豆 Sword jackbeanCanavalia gladiata
H1170 He Zi诃子 Medicine terminaliaTerminalia chebula
H0466 Cai Fu Zi菜菔子 Semen raphaniRaphanus sativus
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H0464 Shi Liu Zi石榴子 NAPunica granatum
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0125 Lai Fu莱菔 Garden radishRaphanus sativus
H0296 Niu Teng牛藤 twotooth achyranthes rootAchyranthes bidentata