Compound Description
Related Targets (Total: 63)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
A | 1 Reference(s) |
| T06MXL | Neprilysin | MME |
P08473 |
A | 1 Reference(s) |
| T40LTN | Phospholipase A2, membrane associated | PLA2G2A |
P14555 |
A | 1 Reference(s) |
| T02WMA | Ornithine decarboxylase | ODC1 |
P11926 |
A | 1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
A | 1 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
A | 1 Reference(s) |
| T64F54 | Mineralocorticoid receptor | NR3C2 |
P08235 |
A | 1 Reference(s) |
| T24G2P | Serum paraoxonase/lactonase 3 (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) | PON3 |
Q15166 |
A | 1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
| T89GFN | Macrophage migration inhibitory factor | MIF |
P14174 |
A | 1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
B | 1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
B | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
C | 1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
C | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
C | 1 Reference(s) |
| T32ECR | Collagen alpha-2(I) chain | COL1A2 |
P08123 |
C | 1 Reference(s) |
| T50E9D | Metallothionein-3 | MT3 |
P25713 |
C | 1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
C | 1 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
C | 1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
C | 1 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
C | 1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
C | 1 Reference(s) |
| T17CNB | Thioredoxin | TXN |
P10599 |
C | 1 Reference(s) |
| T21T2E | Extracellular superoxide dismutase [Cu-Zn] | SOD3 |
P08294 |
C | 1 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
C | 1 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
C | 1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
C | 1 Reference(s) |
| T56MD7 | Glutathione hydrolase 5 proenzyme | GGT5 |
P36269 |
C | 1 Reference(s) |
| T87CV3 | Guanylate cyclase soluble subunit beta-1 | GUCY1B1 |
Q02153 |
C | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
C | 2 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
C | 1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
C | 1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
C | 1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
C | 1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
C | 1 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
C | 1 Reference(s) |
| T11R4S | Tumor necrosis factor receptor superfamily member 5 | CD40 |
P25942 |
C | 1 Reference(s) |
| T47MPW | T-lymphocyte activation antigen CD86 | CD86 |
P42081 |
C | 1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
C | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
C | 1 Reference(s) |
| T30KQB | Alanine aminotransferase 1 | GPT |
P24298 |
C | 1 Reference(s) |
| T42XY2 | Insulin-like growth factor 1 receptor | IGF1R |
P08069 |
C | 1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
C | 1 Reference(s) |
| T02OOS | C-C chemokine receptor type 5 | CCR5 |
P51681 |
C | 1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
C | 1 Reference(s) |
| T26TBJ | Calpain-1 catalytic subunit | CAPN1 |
P07384 |
C | 1 Reference(s) |
| T32EIL | F-box only protein 32 | FBXO32 |
Q969P5 |
C | 1 Reference(s) |
| T92LEW | Inactive caspase-12 | CASP12 |
Q6UXS9 |
C | 1 Reference(s) |
| T96ABY | E3 ubiquitin-protein ligase TRIM63 | TRIM63 |
Q969Q1 |
C | 1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
C | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
C | 1 Reference(s) |
| T02IOG | Cyclin-dependent kinase inhibitor 1B | CDKN1B |
P46527 |
C | 1 Reference(s) |
| T71B0A | Cytosolic phospholipase A2 | PLA2G4A |
P47712 |
C | 1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
C | 2 Reference(s) |
| T33JGV | Tumor suppressor ARF;Cyclin-dependent kinase inhibitor 2A | CDKN2A |
Q8N726;P42771 |
C | 1 Reference(s) |
| T94H37 | Cadherin-1 | CDH1 |
P12830 |
C | 1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
C | 1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
C | 1 Reference(s) |
| T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 |
P05121 |
C | 1 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
C | 1 Reference(s) |
| T40JZG | GPI-anchor transamidase | PIGK |
Q92643 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 47)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0332 | Qiao Mai | 荞麦 | Common buckwheat | Fagopyrum esculentum |
| H0314 | Pu Gong Ying | 蒲公英 | Mongolian dandelion | Taraxacum mongolicum |
| H0967 | Di Er Cao | 地耳草 | Japanese stJohn’swort | Hypericum japonicum |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0466 | Cai Fu Zi | 菜菔子 | Semen raphani | Raphanus sativus |
| H0315 | Pu Gong Ying Jin Gao | 蒲公英浸膏 | Mongolian dandelion | Taraxacum mongolicum |
| H1203 | Hu Ji Sheng | 槲寄生 | Colored mistletoe | Viscum coloratum |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0962 | Dao Dou | 刀豆 | Sword jackbean | Canavalia gladiata |
| H0977 | Bai Bu | 百部 | Tuber stemona | Stemona tuberosa |
| H0987 | Bai Bu Jin Gao | 百部浸膏 | Tuber stemona | Stemona tuberosa |
| H1181 | Hei Zhi Ma | 黑芝麻 | Oriental sesame | Sesamum indicum |
| H1208 | Hu Ma Ren | 胡麻仁 | white seed of oriental sesame | Sesamum indicum |
| H0351 | Quan Shen | 拳参 | Bistort | Polygonum bistorta |
| H1183 | Hong Dou | 红豆 | Hosie ormosia | Ormosia hosiei |
| H0043 | Jie Zi | 芥子 | India mustard seed | Brassica juncea |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0256 | Ming Dang Shen | 明党参 | Medicinal changium | Changium smyrnioides |
| H0709 | Chang Shan | 常山 | Antifebrile dichroa | Dichroa febrifuga |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H1207 | Hu Ma | 胡麻 | white seed of oriental sesame | Sesamum indicum |
| H1170 | He Zi | 诃子 | Medicine terminalia | Terminalia chebula |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0125 | Lai Fu | 莱菔 | Garden radish | Raphanus sativus |
| H1171 | He Zi Rou | 诃子肉 | Medicine terminalia | Terminalia chebula |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0126 | Lai Fu Zi | 莱菔子 | Garden radish seed | Raphanus sativus |
| H0679 | Xing Ren | 杏仁 | Apricot seed | Prunus armeniaca |
| H1152 | Bai Jie Zi | 白芥子 | White mustard seed | Sinapis alba |
| H0296 | Niu Teng | 牛藤 | twotooth achyranthes root | Achyranthes bidentata |
| H0318 | Pu Tao(1) | 蒲桃 | Syzygium | Syzygium jambos |
| H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
| H1244 | Huang Miao | 黄苗 | NA | Taraxacum mongolicum |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0547 | Cang Qing Guo | 藏青果 | Myrobalan | Terminalia chebula |
| H0297 | Niu Xi | 牛膝 | Twotooth achyranthes | Achyranthes bidentata |
| H0982 | Bai Bu Gan Gao | 百部干膏 | Tuber stemona | Stemona tuberosa |
| H0991 | Bai Bu Liu Jin Gao | 百部流浸膏 | Tuber stemona | Stemona tuberosa |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
Ckey description of the interaction between compound and target