Target Description

Type Detail
Target ID T51UV4
Protein Name Trans-acting T-cell-specific transcription factor GATA-3
Uniprot ID P23771
Protein Name Alias GATA-binding factor 3
Gene ID 2625
Gene Symbol GATA3
Gene Alias NA
TTD T92635: Research target
Pfam PF00320
GO
2000352:negative regulation of endothelial cell apoptotic process

1990837:sequence-specific double-stranded DNA binding

0043583:ear development

0016579:protein deubiquitination

0008134:transcription factor binding

0032754:positive regulation of interleukin-5 production

0045582:positive regulation of T cell differentiation

0045064:T-helper 2 cell differentiation

0045599:negative regulation of fat cell differentiation

0060017:parathyroid gland development

2000114:regulation of establishment of cell polarity

0006959:humoral immune response

0001817:regulation of cytokine production

0045087:innate immune response

0002572:pro-T cell differentiation

2000679:positive regulation of transcription regulatory region DNA binding

0048538:thymus development

0002520:immune system development

0009653:anatomical structure morphogenesis

2000607:negative regulation of cell proliferation involved in mesonephros development

0019221:cytokine-mediated signaling pathway

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0008584:male gonad development

0006952:defense response

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

0061085:regulation of histone H3-K27 methylation

0010595:positive regulation of endothelial cell migration

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045471:response to ethanol

0010719:negative regulation of epithelial to mesenchymal transition

0070888:E-box binding

0048646:anatomical structure formation involved in morphogenesis

2000611:positive regulation of thyroid hormone generation

0060676:ureteric bud formation

0005134:interleukin-2 receptor binding

0007596:blood coagulation

0042802:identical protein binding

0060231:mesenchymal to epithelial transition

0032753:positive regulation of interleukin-4 production

0072197:ureter morphogenesis

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0060037:pharyngeal system development

0072178:nephric duct morphogenesis

0045165:cell fate commitment

0001822:kidney development

0035162:embryonic hemopoiesis

0002088:lens development in camera-type eye

0009967:positive regulation of signal transduction

0051569:regulation of histone H3-K4 methylation

0035457:cellular response to interferon-alpha

0032703:negative regulation of interleukin-2 production

0006338:chromatin remodeling

0045061:thymic T cell selection

2000734:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

2000703:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation

0048589:developmental growth

0014065:phosphatidylinositol 3-kinase signaling

1902036:regulation of hematopoietic stem cell differentiation

0032689:negative regulation of interferon-gamma production

0001709:cell fate determination

0009615:response to virus

0031929:TOR signaling

0061290:canonical Wnt signaling pathway involved in metanephric kidney development

0033600:negative regulation of mammary gland epithelial cell proliferation

0050852:T cell receptor signaling pathway

0000122:negative regulation of transcription by RNA polymerase II

0051897:positive regulation of protein kinase B signaling

0006357:regulation of transcription by RNA polymerase II

0030217:T cell differentiation

0000976:transcription regulatory region sequence-specific DNA binding

2000553:positive regulation of T-helper 2 cell cytokine production

0032736:positive regulation of interleukin-13 production

0042493:response to drug

0071773:cellular response to BMP stimulus

0003215:cardiac right ventricle morphogenesis

0060374:mast cell differentiation

0010975:regulation of neuron projection development

0043627:response to estrogen

0001823:mesonephros development

0090102:cochlea development

0071353:cellular response to interleukin-4

0072107:positive regulation of ureteric bud formation

1902895:positive regulation of pri-miRNA transcription by RNA polymerase II

1901536:negative regulation of DNA demethylation

0005654:nucleoplasm

0045786:negative regulation of cell cycle

0001806:type IV hypersensitivity

0003677:DNA binding

0048485:sympathetic nervous system development

0008270:zinc ion binding

0071442:positive regulation of histone H3-K14 acetylation

0045944:positive regulation of transcription by RNA polymerase II

0050728:negative regulation of inflammatory response

0005634:nucleus

2000146:negative regulation of cell motility

0007411:axon guidance

0071356:cellular response to tumor necrosis factor

0007165:signal transduction

0003180:aortic valve morphogenesis

0008285:negative regulation of cell population proliferation

0072676:lymphocyte migration

0048568:embryonic organ development

0042421:norepinephrine biosynthetic process

0043523:regulation of neuron apoptotic process

0042472:inner ear morphogenesis

0009791:post-embryonic development

0071599:otic vesicle development

0001764:neuron migration

0035898:parathyroid hormone secretion

0043370:regulation of CD4-positive, alpha-beta T cell differentiation

0072179:nephric duct formation

0010332:response to gamma radiation

0001701:in utero embryonic development

0030856:regulation of epithelial cell differentiation

2000683:regulation of cellular response to X-ray

0045893:positive regulation of transcription, DNA-templated

0060065:uterus development

0048469:cell maturation

0000785:chromatin

0003700:DNA-binding transcription factor activity

0030218:erythrocyte differentiation

2000617:positive regulation of histone H3-K9 acetylation

0000987:cis-regulatory region sequence-specific DNA binding

0035799:ureter maturation

0045892:negative regulation of transcription, DNA-templated

0072182:regulation of nephron tubule epithelial cell differentiation

0071837:HMG box domain binding

0003281:ventricular septum development

PDB 4HCA ; 4HC7 ; 4HC9
Drugbank NA
KEGG hsa:2625

Related Compounds  (Total: 4)

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C0035
Name: Dronabinol
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C0226
Name: Morphine
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C0668
Name: Platycodin D
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C1106
Name: shikonin


Related Herbs  (Total: 6)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0204 Ma Ren麻仁 NACannabis sativa
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0248 Mi Ying Su Ke蜜罂粟壳 Opium poppyPapaver somniferum
H0757 Ying Su Ke罂粟壳 Opium poppy pericarpPapaver somniferum
H0756 Ying Su罂粟 Opium poppyPapaver somniferum
H0036 Jie Geng桔梗 BalloonflowerPlatycodon grandiflorum