Target Description

Type Detail
Target ID T53FD0
Protein Name Leptin receptor
Uniprot ID P48357
Protein Name Alias LEP-R;  HuB219;  OB receptor;  OB-R;  CD antigen CD295
Gene ID 3953
Gene Symbol LEPR
Gene Alias DB;  OBR
TTD T17163: Successful target
Pfam PF18589 ; PF06328
GO
0098868:bone growth

0030217:T cell differentiation

0016021:integral component of membrane

0120162:positive regulation of cold-induced thermogenesis

0150104:transport across blood-brain barrier

0045721:negative regulation of gluconeogenesis

0006112:energy reserve metabolic process

0051049:regulation of transport

0038021:leptin receptor activity

0016323:basolateral plasma membrane

0001525:angiogenesis

0017046:peptide hormone binding

0007275:multicellular organism development

0001934:positive regulation of protein phosphorylation

0004896:cytokine receptor activity

0042802:identical protein binding

0097009:energy homeostasis

0009897:external side of plasma membrane

0005576:extracellular region

0033210:leptin-mediated signaling pathway

0051346:negative regulation of hydrolase activity

0007166:cell surface receptor signaling pathway

0019955:cytokine binding

0008203:cholesterol metabolic process

0042593:glucose homeostasis

0044321:response to leptin

0005977:glycogen metabolic process

0043235:receptor complex

0014009:glial cell proliferation

0019221:cytokine-mediated signaling pathway

0004888:transmembrane signaling receptor activity

0046850:regulation of bone remodeling

0010507:negative regulation of autophagy

0060259:regulation of feeding behavior

0019953:sexual reproduction

0006909:phagocytosis

PDB 3V6O ; 6E2P
Drugbank DB05098 ; DB09046
KEGG hsa:3953

Related Compounds  (Total: 2)

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C0055
Name: Estradiol
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C1017
Name: puerarin


Related Herbs  (Total: 17)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0077 Jiu EthanolVinum
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0847 Zi He Che紫河车 Human placentaHomo sapiens