HIT-result

Target Description

Type	Detail
Target ID	T60I6V
Protein Name	E3 SUMO-protein ligase PIAS3
Uniprot ID	Q9Y6X2
Protein Name Alias	EC 2.3.2.-; E3 SUMO-protein transferase PIAS3; Protein inhibitor of activated STAT protein 3
Gene ID	10401
Gene Symbol	PIAS3
Gene Alias	NA
TTD	NA
Pfam	PF02891 ; PF14324
GO	0033235:positive regulation of protein sumoylation 0030425:dendrite 0045671:negative regulation of osteoclast differentiation 0071847:TNFSF11-mediated signaling pathway 0008022:protein C-terminus binding 0019789:SUMO transferase activity 0009725:response to hormone 0015459:potassium channel regulator activity 0003712:transcription coregulator activity 0045202:synapse 0005737:cytoplasm 0005654:nucleoplasm 0019899:enzyme binding 0008270:zinc ion binding 0045838:positive regulation of membrane potential 0033234:negative regulation of protein sumoylation 0016607:nuclear speck 0001085:RNA polymerase II transcription factor binding 0061665:SUMO ligase activity 0010628:positive regulation of gene expression 0000122:negative regulation of transcription by RNA polymerase II 0016925:protein sumoylation 0047485:protein N-terminus binding 0006357:regulation of transcription by RNA polymerase II
PDB	4MVT
Drugbank	NA
KEGG	hsa:10401

Type

Detail

Target ID

T60I6V

Protein Name

E3 SUMO-protein ligase PIAS3

Uniprot ID

Q9Y6X2

Protein Name Alias

EC 2.3.2.-; E3 SUMO-protein transferase PIAS3; Protein inhibitor of activated STAT protein 3

Gene ID

10401

Gene Symbol

PIAS3

Gene Alias

TTD

Pfam

PF02891 ; PF14324

0033235:positive regulation of protein sumoylation

0030425:dendrite

0045671:negative regulation of osteoclast differentiation

0071847:TNFSF11-mediated signaling pathway

0008022:protein C-terminus binding

0019789:SUMO transferase activity

0009725:response to hormone

0015459:potassium channel regulator activity

0003712:transcription coregulator activity

0045202:synapse

0005737:cytoplasm

0005654:nucleoplasm

0019899:enzyme binding

0008270:zinc ion binding

0045838:positive regulation of membrane potential

0033234:negative regulation of protein sumoylation

0016607:nuclear speck

0001085:RNA polymerase II transcription factor binding

0061665:SUMO ligase activity

0010628:positive regulation of gene expression

0000122:negative regulation of transcription by RNA polymerase II

0016925:protein sumoylation

0047485:protein N-terminus binding

0006357:regulation of transcription by RNA polymerase II

PDB

4MVT

Drugbank

KEGG

hsa:10401

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Name: Morin

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Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione

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Name: Morin

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Name: Curcumin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 12)