Target Description

Type Detail
Target ID T67GDP
Protein Name Aryl hydrocarbon receptor nuclear translocator-like protein 1
Uniprot ID O00327
Protein Name Alias Basic-helix-loop-helix-PAS protein MOP3;  Brain and muscle ARNT-like 1;  Class E basic helix-loop-helix protein 5;  bHLHe5;  Member of PAS protein 3;  PAS domain-containing protein 3;  bHLH-PAS protein JAP3
Gene ID 406
Gene Symbol ARNTL
Gene Alias BHLHE5;  BMAL1;  MOP3;  PASD3
TTD NA
Pfam PF00989 ; PF00010
GO
0003677:DNA binding

0005634:nucleus

2000772:regulation of cellular senescence

0032007:negative regulation of TOR signaling

0017162:aryl hydrocarbon receptor binding

0043565:sequence-specific DNA binding

0006355:regulation of transcription, DNA-templated

0120163:negative regulation of cold-induced thermogenesis

0140297:DNA-binding transcription factor binding

0045892:negative regulation of transcription, DNA-templated

0016605:PML body

0051775:response to redox state

0043161:proteasome-mediated ubiquitin-dependent protein catabolic process

0050796:regulation of insulin secretion

0033391:chromatoid body

2000323:negative regulation of glucocorticoid receptor signaling pathway

0042753:positive regulation of circadian rhythm

1901985:positive regulation of protein acetylation

0051879:Hsp90 protein binding

0032922:circadian regulation of gene expression

0043231:intracellular membrane-bounded organelle

0000785:chromatin

0070888:E-box binding

0000976:transcription regulatory region sequence-specific DNA binding

2001016:positive regulation of skeletal muscle cell differentiation

0046983:protein dimerization activity

0042634:regulation of hair cycle

0005667:transcription regulator complex

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045893:positive regulation of transcription, DNA-templated

2000074:regulation of type B pancreatic cell development

0090403:oxidative stress-induced premature senescence

0006357:regulation of transcription by RNA polymerase II

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

1990837:sequence-specific double-stranded DNA binding

0051726:regulation of cell cycle

0050767:regulation of neurogenesis

0007623:circadian rhythm

0045599:negative regulation of fat cell differentiation

0045944:positive regulation of transcription by RNA polymerase II

0034751:aryl hydrocarbon receptor complex

0090263:positive regulation of canonical Wnt signaling pathway

0007283:spermatogenesis

PDB 4H10
Drugbank NA
KEGG hsa:406

Related Compounds  (Total: 2)

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C0210
Name: Melatonin
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C0401
Name: Shikonin


Related Herbs  (Total: 6)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0986 Dian Zi Cao滇紫草 Paniculate onosmaOnosma paniculatum
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0673 Xin Jiang Zi Cao新疆紫草 Arnebia rootArnebia euchroma