HIT-result

Type	Detail
Target ID	T67GDP
Protein Name	Aryl hydrocarbon receptor nuclear translocator-like protein 1
Uniprot ID	O00327
Protein Name Alias	Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3
Gene ID	406
Gene Symbol	ARNTL
Gene Alias	BHLHE5; BMAL1; MOP3; PASD3
TTD	NA
Pfam	PF00989 ; PF00010
GO	0003677:DNA binding 0005634:nucleus 2000772:regulation of cellular senescence 0032007:negative regulation of TOR signaling 0017162:aryl hydrocarbon receptor binding 0043565:sequence-specific DNA binding 0006355:regulation of transcription, DNA-templated 0120163:negative regulation of cold-induced thermogenesis 0140297:DNA-binding transcription factor binding 0045892:negative regulation of transcription, DNA-templated 0016605:PML body 0051775:response to redox state 0043161:proteasome-mediated ubiquitin-dependent protein catabolic process 0050796:regulation of insulin secretion 0033391:chromatoid body 2000323:negative regulation of glucocorticoid receptor signaling pathway 0042753:positive regulation of circadian rhythm 1901985:positive regulation of protein acetylation 0051879:Hsp90 protein binding 0032922:circadian regulation of gene expression 0043231:intracellular membrane-bounded organelle 0000785:chromatin 0070888:E-box binding 0000976:transcription regulatory region sequence-specific DNA binding 2001016:positive regulation of skeletal muscle cell differentiation 0046983:protein dimerization activity 0042634:regulation of hair cycle 0005667:transcription regulator complex 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 2000074:regulation of type B pancreatic cell development 0090403:oxidative stress-induced premature senescence 0006357:regulation of transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 1990837:sequence-specific double-stranded DNA binding 0051726:regulation of cell cycle 0050767:regulation of neurogenesis 0007623:circadian rhythm 0045599:negative regulation of fat cell differentiation 0045944:positive regulation of transcription by RNA polymerase II 0034751:aryl hydrocarbon receptor complex 0090263:positive regulation of canonical Wnt signaling pathway 0007283:spermatogenesis
PDB	4H10
Drugbank	NA
KEGG	hsa:406

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H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
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