HIT-result

Target Description

Type	Detail
Target ID	T69NNS
Protein Name	PRKC apoptosis WT1 regulator protein
Uniprot ID	Q96IZ0
Protein Name Alias	Prostate apoptosis response 4 protein; Par-4
Gene ID	5074
Gene Symbol	PAWR
Gene Alias	PAR4
TTD	T00496: Clinical Trial target
Pfam	NA
GO	2000774:positive regulation of cellular senescence 1901300:positive regulation of hydrogen peroxide-mediated programmed cell death 0097190:apoptotic signaling pathway 0051017:actin filament bundle assembly 0048147:negative regulation of fibroblast proliferation 0030889:negative regulation of B cell proliferation 0042986:positive regulation of amyloid precursor protein biosynthetic process 0050860:negative regulation of T cell receptor signaling pathway 0043065:positive regulation of apoptotic process 0006915:apoptotic process 0005886:plasma membrane 0003714:transcription corepressor activity 0015629:actin cytoskeleton 0019899:enzyme binding 0042130:negative regulation of T cell proliferation 0005737:cytoplasm 0043522:leucine zipper domain binding 0005634:nucleus 0003779:actin binding 0010628:positive regulation of gene expression 0000785:chromatin 0000122:negative regulation of transcription by RNA polymerase II
PDB	2JK9
Drugbank	NA
KEGG	hsa:5074

Type

Detail

Target ID

T69NNS

Protein Name

PRKC apoptosis WT1 regulator protein

Uniprot ID

Q96IZ0

Protein Name Alias

Prostate apoptosis response 4 protein; Par-4

Gene ID

5074

Gene Symbol

PAWR

Gene Alias

PAR4

TTD

T00496: Clinical Trial target

Pfam

2000774:positive regulation of cellular senescence

1901300:positive regulation of hydrogen peroxide-mediated programmed cell death

0097190:apoptotic signaling pathway

0051017:actin filament bundle assembly

0048147:negative regulation of fibroblast proliferation

0030889:negative regulation of B cell proliferation

0042986:positive regulation of amyloid precursor protein biosynthetic process

0050860:negative regulation of T cell receptor signaling pathway

0043065:positive regulation of apoptotic process

0006915:apoptotic process

0005886:plasma membrane

0003714:transcription corepressor activity

0015629:actin cytoskeleton

0019899:enzyme binding

0042130:negative regulation of T cell proliferation

0005737:cytoplasm

0043522:leucine zipper domain binding

0005634:nucleus

0003779:actin binding

0010628:positive regulation of gene expression

0000785:chromatin

0000122:negative regulation of transcription by RNA polymerase II

PDB

2JK9

Drugbank

KEGG

hsa:5074

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0077	Jiu	酒	Ethanol	Vinum
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 17)