Target Description

Type Detail
Target ID T69PZ6
Protein Name Protein phosphatase 1 regulatory subunit 12A
Uniprot ID O14974
Protein Name Alias Myosin phosphatase-targeting subunit 1;  Myosin phosphatase target subunit 1;  Protein phosphatase myosin-binding subunit
Gene ID 4659
Gene Symbol PPP1R12A
Gene Alias MBS;  MYPT1
TTD NA
Pfam PF15898 ; PF12796
GO
0046822:regulation of nucleocytoplasmic transport

0005813:centrosome

0005925:focal adhesion

0019208:phosphatase regulator activity

0005829:cytosol

0043086:negative regulation of catalytic activity

0035507:regulation of myosin-light-chain-phosphatase activity

0006470:protein dephosphorylation

0035690:cellular response to drug

0007098:centrosome cycle

0004857:enzyme inhibitor activity

0005737:cytoplasm

0031672:A band

0043292:contractile fiber

0035508:positive regulation of myosin-light-chain-phosphatase activity

0019901:protein kinase binding

0005886:plasma membrane

0030018:Z disc

0030155:regulation of cell adhesion

0005730:nucleolus

0071889:14-3-3 protein binding

0015629:actin cytoskeleton

0000776:kinetochore

0007165:signal transduction

0000278:mitotic cell cycle

0000086:G2/M transition of mitotic cell cycle

0005654:nucleoplasm

0072357:PTW/PP1 phosphatase complex

0045944:positive regulation of transcription by RNA polymerase II

PDB 2KJY ; 5HUZ
Drugbank NA
KEGG hsa:4659

Related Compounds  (Total: 1)

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C0247
Name: Nicotine


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0476 Can E蚕蛾 SilkwormBombyx mori
H0490 Can Jian蚕茧 Silk cocoonBombyx mori
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0495 Can Sha蚕砂 Silkworm excrementBombyx mori
H0500 Can Yong蚕蛹 Silkworm chrysalisBombyx mori
H1134 Bai Jiang Can白僵蚕 Silkworm larvaBombyx mori
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H1133 Gui Jian Yu鬼箭羽 Winged euonymusEuonymus alatus