HIT-result

Target Description

Type	Detail
Target ID	T78MBM
Protein Name	Transcription factor 4
Uniprot ID	P15884
Protein Name Alias	TCF-4; Class B basic helix-loop-helix protein 19; bHLHb19; Immunoglobulin transcription factor 2; ITF-2; SL3-3 enhancer factor 2; SEF-2
Gene ID	6925
Gene Symbol	TCF4
Gene Alias	BHLHB19; ITF2; SEF2
TTD	NA
Pfam	PF00010
GO	0003677:DNA binding 0042802:identical protein binding 0005634:nucleus 0001093:TFIIB-class transcription factor binding 1990907:beta-catenin-TCF complex 0007399:nervous system development 0070369:beta-catenin-TCF7L2 complex 0030154:cell differentiation 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0000785:chromatin 0070888:E-box binding 0065004:protein-DNA complex assembly 0005667:transcription regulator complex 0045666:positive regulation of neuron differentiation 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 0003700:DNA-binding transcription factor activity 0006357:regulation of transcription by RNA polymerase II 0008022:protein C-terminus binding 0046982:protein heterodimerization activity 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 1990837:sequence-specific double-stranded DNA binding 0045944:positive regulation of transcription by RNA polymerase II 0008013:beta-catenin binding
PDB	6OD5 ; 6OD4 ; 6OD3 ; 2KWF
Drugbank	NA
KEGG	hsa:6925

Type

Detail

Target ID

T78MBM

Protein Name

Transcription factor 4

Uniprot ID

P15884

Protein Name Alias

TCF-4; Class B basic helix-loop-helix protein 19; bHLHb19; Immunoglobulin transcription factor 2; ITF-2; SL3-3 enhancer factor 2; SEF-2

Gene ID

6925

Gene Symbol

TCF4

Gene Alias

BHLHB19; ITF2; SEF2

TTD

Pfam

PF00010

0003677:DNA binding

0042802:identical protein binding

0005634:nucleus

0001093:TFIIB-class transcription factor binding

1990907:beta-catenin-TCF complex

0007399:nervous system development

0070369:beta-catenin-TCF7L2 complex

0030154:cell differentiation

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0000785:chromatin

0070888:E-box binding

0065004:protein-DNA complex assembly

0005667:transcription regulator complex

0045666:positive regulation of neuron differentiation

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045893:positive regulation of transcription, DNA-templated

0003700:DNA-binding transcription factor activity

0006357:regulation of transcription by RNA polymerase II

0008022:protein C-terminus binding

0046982:protein heterodimerization activity

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

1990837:sequence-specific double-stranded DNA binding

0045944:positive regulation of transcription by RNA polymerase II

0008013:beta-catenin binding

PDB

6OD5 ; 6OD4 ; 6OD3 ; 2KWF

Drugbank

KEGG

hsa:6925

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0416	Shan Shen	山参	NA	Panax ginseng
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 25)