Target Description
| Type | Detail |
|---|---|
| Target ID | T87TVN |
| Protein Name | Toll-like receptor 5 |
| Uniprot ID |
O60602 |
| Protein Name Alias | Toll/interleukin-1 receptor-like protein 3 |
| Gene ID |
7100 |
| Gene Symbol | TLR5 |
| Gene Alias | TIL3 |
| TTD | T43718: Clinical Trial target |
| Pfam | PF13855 ; PF01582 |
| GO |
0004888:transmembrane signaling receptor activity
0002755:MyD88-dependent toll-like receptor signaling pathway 0038023:signaling receptor activity 0005887:integral component of plasma membrane 0034146:toll-like receptor 5 signaling pathway 0071260:cellular response to mechanical stimulus 0002224:toll-like receptor signaling pathway 0042742:defense response to bacterium 0006954:inflammatory response 0034123:positive regulation of toll-like receptor signaling pathway 0005149:interleukin-1 receptor binding 0032757:positive regulation of interleukin-8 production 0045087:innate immune response 0005886:plasma membrane |
| PDB | 3J0A ; 1P95 |
| Drugbank | NA |
| KEGG | hsa:7100 |
Related Herbs (Total: 23)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0437 | She Xiang | 麝香 | Abelmusk | Moschus moschiferus |
| H0235 | Mao She Xiang | 毛麝香 | Abelmusk | Moschus moschiferus |
| H0236 | Mao She Xiang Jin Gao | 毛麝香浸膏 | Abelmusk | Moschus moschiferus |
| H0520 | Tai Pan Fen | 胎盘粉 | Fetus powder | Human placenta |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0385 | San Qi Ye Jing | 三七叶茎 | Sanchi | Panax notoginseng |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0356 | Ren Gong She Xiang | 人工麝香 | Abelmusk | Moschus moschiferus |
| H0382 | San Qi Hua | 三七花 | Sanchi | Panax notoginseng |
| H0370 | Ru Xiang | 乳香 | Olibanum | Boswellia carterii |
| H1102 | Gu Sui Bu | 骨碎补 | Fortune’s drynaria rhizome | Drynaria fortunei |
| H0077 | Jiu | 酒 | Ethanol | Vinum |
| H0697 | Ya Ma Zi | 亚麻子 | Common flax seed | Linum usitatissimum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0521 | Tai Pan Zu Zhi Fen | 胎盘组织粉 | NA | Human placenta |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0661 | Xiao Hei Dou | 小黑豆 | Black turtle bean | Phaseolus vulgaris |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0383 | San Qi Jing Ye | 三七茎叶 | Sanchi | Panax notoginseng |
| H0384 | San Qi Ye | 三七叶 | Folium panax notoginseng | Panax notoginseng |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0380 | San Qi Gan Jin Gao | 三七干浸膏 | Sanchi | Panax notoginseng |
| H0381 | San Qi Gao Fen | 三七膏粉 | Sanchi | Panax notoginseng |