Compound Description

ID:   C0077 Common name:   Flavone
IUPAC:  2-phenylchromen-4-one CAS:  CAS:525-82-6
Chembl ID:   CHEMBL275638 Pubchem ID:   CID:10680
Formula:  C15H10O2 TCM-ID:  TCMC1179
Smiles:  C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2
Alias:

Flavone;

2-Phenyl-4H-1-benzopyran-4-one;

2-Phenyl-4-chromone;

2-Phenyl-4H-benzopyran-4-one;

2-Phenyl-4H-chromen-4-one;

2-Phenyl-γ-benzopyrone;

2-Phenylchromen-4-one;

2-Phenylchromone;

94166III;

Asmacoril;

Chromocor;

Cromaril;

NSC 19028
Structure:

Related Targets  (Total: 14)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
A 1 Reference(s)
T23P74 Caspase-9CASP9 P55211
B 1 Reference(s)
T90SGJ Caspase-2CASP2 P42575
B 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
B 1 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
B 1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
B 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
B 1 Reference(s)
T52YQN Caspase-10CASP10 Q92851
B 1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
B 1 Reference(s)
T27M4K Rho GTPase-activating protein 7DLC1 Q96QB1
C 1 Reference(s)
T64W2K Cyclin-dependent kinase inhibitor 1CDKN1A P38936
C 1 Reference(s)
T52ARL Suppressor of cytokine signaling 3SOCS3 O14543
C 1 Reference(s)
T08VHE Probable threonine protease PRSS50PRSS50 Q9UI38
C 1 Reference(s)
T85NRC Pyruvate kinase PKMPKM P14618
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 13)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0700 Ya Zhi Cao鸭跖草 Common dayflowerCommelina communis
H0550 Tie Bang Chui Ye铁棒锤叶 Leaf of pendulous monkshoodFolium aconiti szechenyiani
H0092 Ju Hua菊花 Florists chrysanthemum flowerChrysanthemum morifolium
H0347 Qing Pi青皮 Green tangerine peelPericarpium citri reticulatae viride
H0976 Di Qing Pi地青皮 NAPericarpium citri reticulatae viride
H0078 Jiu Bi Ying救必应 Ovateleaf hollyIlex rotunda
H0667 Xiao Qing Pi小青皮 Green tangerine peelPericarpium citri reticulatae viride
H0388 San Ye Qing三叶青 Hemsley rockvine rootRadix tetrastigmatis hemsleyani
H0820 Chong Lou重楼 Paris rootRhizoma paridis
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0695 Ya Dan Zi鸦胆子 Java bruceaBrucea javanica
H1161 Hang Ju杭菊 Chrysanthemum flowerChrysanthemum morifolium
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum