Compound Description
| ID: C0124 | Common name: Hispidulin |
| IUPAC: 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one | CAS: CAS:1447-88-7 |
| Chembl ID: CHEMBL293776 | Pubchem ID: CID:5281628 |
| Formula: C16H12O6 | TCM-ID: TCMC1329 |
| Smiles: COc1c(O)cc2c(c1O)c(=O)cc(o2)c1ccc(cc1)O | |
| Alias:
Flavone, 4',5,7-trihydroxy-6-methoxy-;
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-6-methoxyflavone; 5,7,4'-Trihydroxy-6-methoxyflavone; 6-Methoxy-5,7,4'-trihydroxyflavone; 6-Methoxyapigenin; 6-Methylscutellarein; 6-O-Methylscutellarein; Dinatin; Hispedulin; Hispidulin; Hispiludin; NSC 122415; Salvitin; Scutellarein 6-methyl ether |
Structure:
|
Related Targets (Total: 2)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
A | 1 Reference(s) |
| T37BP1 | Serine/threonine-protein kinase pim-1 | PIM1 |
P11309 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 49)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0969 | Di Fu Zi | 地肤子 | fruit of belvedere | Fructus kochiae |
| H0476 | Can E | 蚕蛾 | Silkworm | Bombyx mori |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0500 | Can Yong | 蚕蛹 | Silkworm chrysalis | Bombyx mori |
| H0663 | Xiao Ji | 小蓟 | Setose thistle | Cirsium setosum |
| H0727 | Ye Gan Cao | 野甘草 | Sweet broomwort | Scoparia dulcis |
| H0757 | Ying Su Ke | 罂粟壳 | Opium poppy pericarp | Papaver somniferum |
| H0248 | Mi Ying Su Ke | 蜜罂粟壳 | Opium poppy | Papaver somniferum |
| H0524 | Tan Xiang | 檀香 | Sandalwood | Santalum album |
| H0648 | Xiang Si Teng | 相思藤 | Coralhead plant vine | Abrus precatorius |
| H0930 | Da Ji Gen | 大蓟根 | NA | Herba cirsii japonici |
| H0546 | Tian Shan Xue Lian Hua | 天山雪莲花 | NA | Saussurea involucrata |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H0495 | Can Sha | 蚕砂 | Silkworm excrement | Bombyx mori |
| H0933 | Da Ji(1) | 大蓟 | NA | Herba cirsii japonici |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0756 | Ying Su | 罂粟 | Opium poppy | Papaver somniferum |
| H0713 | Che Qian Cao | 车前草 | all-grass of rippleseed plantain | Plantago depressa |
| H0690 | Xue Lian | 雪莲 | Snow lotus | Saussurea involucrata |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
| H1100 | Gu Jing Cao | 谷精草 | Pipewart | Eriocaulon buergerianum |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H0931 | Da Ji Gen Jin Gao | 大蓟根浸膏 | NA | Herba cirsii japonici |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0686 | Xuan Fu Hua | 旋覆花 | Inula flower | Flos inulae |
| H1134 | Bai Jiang Can | 白僵蚕 | Silkworm larva | Bombyx mori |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0691 | Xue Lian Hua | 雪莲花 | Snow lotus | Saussurea involucrata |
| H1020 | E Bu Shi Cao Nong Suo Ye | 鹅不食草浓缩液 | Small centipeda | Centipeda minima |
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H0496 | Shui Ze Lan | 水泽兰 | NA | Lycopus lucidus |
| H1019 | E Bu Shi Cao | 鹅不食草 | Small centipeda | Centipeda minima |
| H0490 | Can Jian | 蚕茧 | Silk cocoon | Bombyx mori |
| H0649 | Xiang Si Zi | 相思子 | Coralhead plant | Abrus precatorius |
| H1190 | Hong Lian | 洪连 | all-grass of shorttube lagotis | Herba lagotidis |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0164 | Ban Zhi Lian | 半枝莲 | Barbed skullcap | Scutellaria barbata |
Ckey description of the interaction between compound and target