Compound Description
| ID: C0162 | Common name: Jatrorrhizine |
| IUPAC: 2,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol | CAS: NA |
| Chembl ID: CHEMBL251055 | Pubchem ID: CID:72323 |
| Formula: C20H19NO4 | TCM-ID: TCMC1424 |
| Smiles: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T76SUY | Solute carrier family 22 member 2 | SLC22A2 |
O15244 |
A | 1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
B | 1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 23)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1242 | Huang Lian Gan Jin Gao | 黄连干浸膏 | Coptis deltoidea | Coptis chinensis |
| H1115 | Guan Huang Bai | 关黄柏 | Amur cork tree | Phellodendron amurense |
| H0706 | Yan Hu Suo | 延胡索 | Yanhusuo | Corydalis yanhusuo |
| H1230 | Huang Bai Fen | 黄柏粉 | Amur corktree | Phellodendron amurense |
| H0656 | Xiao Bo Gen | 小檗根 | Barberry root | Berberis julianae |
| H1033 | Fang Ji | 防己 | Fourstamen stephania | Stephania tetrandra |
| H0376 | San Ke Zhen Pi | 三棵针皮 | root or bark of reddrop barberry | Cortex berberidis |
| H0029 | Jiang Huang Lian | 姜黄连 | Coptis deltoidea | Coptis chinensis |
| H0704 | Yan Guan Huang Bai | 盐关黄柏 | Amur cork tree | Phellodendron amurense |
| H0760 | Yu Huang Lian | 萸黄连 | Coptis deltoidea | Coptis chinensis |
| H0682 | Xiong Huang Lian | 雄黄连 | Coptis deltoidea | Coptis chinensis |
| H0785 | Ze Xi Huang Lian | 择细黄连 | Coptis deltoidea | Coptis chinensis |
| H1228 | Huang Bai | 黄柏 | Amur corktree | Phellodendron amurense |
| H0205 | Ma Wei Lian | 马尾连 | Manyleaf meadowrue | Thalictrum foliolosum |
| H0051 | Jin Guo Lan | 金果榄 | Hairystalk tinospora | Tinospora capillipes |
| H0167 | Long Xian Xiang | 龙涎香 | Ammbergris | Physeter catodon |
| H0872 | Chuan Huang Lian | 川黄连 | rhizome of chinese goldthread | Coptis chinensis |
| H1243 | Huang Lian Xu | 黄连须 | Coptis deltoidea | Coptis chinensis |
| H1241 | Huang Lian | 黄连 | Coptis deltoidea | Coptis chinensis |
| H0633 | Xia Tian Wu | 夏天无 | Decumbent corydalis | Corydalis decumbens |
| H1231 | Huang Bai Tan | 黄柏炭 | Amur corktree | Phellodendron amurense |
| H0082 | Jiu Huang Lian | 酒黄连 | Coptis deltoidea | Coptis chinensis |
| H0375 | San Ke Zhen | 三棵针 | root or bark of reddrop barberry | Cortex berberidis |
Ckey description of the interaction between compound and target