Compound Description
| ID: C1177 | Common name: Beta Carotene |
| IUPAC: 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene | CAS: NA |
| Chembl ID: CHEMBL1293 | Pubchem ID: CID:5280489 |
| Formula: C40H56 | TCM-ID: TCMC791 |
| Smiles: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 23)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T45XTW | Retinoic acid receptor RXR-alpha | RXRA |
P19793 |
A | 1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
B | 1 Reference(s) |
| T95H9O | Stromelysin-2 | MMP10 |
P09238 |
B | 1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
B | 1 Reference(s) |
| T83TMF | Cytochrome P450 2B1 | Cyp2b1 |
P00176 |
B | 1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
B | 1 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
B | 1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
B | 1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
B | 1 Reference(s) |
| T80PUR | Caspase-7 | CASP7 |
P55210 |
B | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
C | 1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
C | 1 Reference(s) |
| T34X07 | CCAAT/enhancer-binding protein alpha | CEBPA |
P49715 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
C | 1 Reference(s) |
| T18YXD | Albumin | ALB |
P02768 |
C | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
C | 1 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
C | 1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
C | 1 Reference(s) |
| T63YAO | Caveolin-1 | CAV1 |
Q03135 |
C | 1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 67)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0264 | Mu Bie Zi | 木鳖子 | Cochinhina momordica seed | Momordica cochinchinensis |
| H0693 | Xue Xie | 血蝎 | Dragon's blood | Daemonorops draco |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H0332 | Qiao Mai | 荞麦 | Common buckwheat | Fagopyrum esculentum |
| H0500 | Can Yong | 蚕蛹 | Silkworm chrysalis | Bombyx mori |
| H1134 | Bai Jiang Can | 白僵蚕 | Silkworm larva | Bombyx mori |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0095 | Gou Qi Zi | 枸杞子 | Chinese wolfberry fruit | Lycium chinense |
| H0121 | La Jiao Jin Chu Ye | 辣椒浸出液 | Bush redpepper | Capsicum frutescens |
| H0189 | Lv Cha | 绿茶 | Green tea | Folium camelliae sinensis |
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0158 | Liu Ling Ju | 六棱菊 | NA | Laggera alata |
| H0621 | Xi Gua Cui Yi | 西瓜翠衣 | NA | Citrullus lanatus |
| H0604 | Wu Wei Teng | 五味藤 | NA | Securidaca inappendiculata |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H0094 | Gou Qi | 枸杞 | Chinese wolfberry fruit | Lycium chinense |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0490 | Can Jian | 蚕茧 | Silk cocoon | Bombyx mori |
| H1059 | Fu Shen | 茯神 | Indian bread with pine | Poria |
| H0623 | Xi Hong Hua | 西红花 | Saffron | Stigma croci |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0395 | Sang Shen Qing Gao | 桑葚清膏 | Mulberry | Morus alba |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0495 | Can Sha | 蚕砂 | Silkworm excrement | Bombyx mori |
| H1205 | Hu Lu Cha | 葫芦茶 | Triquetrous tadehagi | Tadehagi triquetrum |
| H0736 | Yi Dian Hong | 一点红 | Sowthistle tasselflower | Emilia sonchifolia |
| H1145 | Hai Dai | 海带 | Ellgrass | Zostera marina |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0719 | Chen Pi | 陈皮 | Dried tangerine peel | Pericarpium citri reticulatae |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
| H0866 | Chuan Bi Xie | 川萆薢 | Sichuan castor seed | Dioscorea septemloba |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H0775 | Yun Zhi | 云芝 | Coriolus versicolor | Polysaccharidum versicolor |
| H0940 | Da Ye Zi Zhu | 大叶紫珠 | Bigleaf beautyberry | Callicarpa macrophylla |
| H0394 | Sang Shen Jin Gao | 桑葚浸膏 | Mulberry | Morus alba |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0122 | La Jiao Jin Gao | 辣椒浸膏 | Bush redpepper | Capsicum frutescens |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0119 | La Jiao | 辣椒 | Bush redpepper | Capsicum frutescens |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0849 | Zi Su Geng | 紫苏梗 | Common perilla stem | Perilla frutescens var. arguta |
| H0075 | Jing Mi | 粳米 | Rice | Oryza sativa |
| H0123 | La Jiao Liu Jin Gao | 辣椒流浸膏 | Bush redpepper | Capsicum frutescens |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0476 | Can E | 蚕蛾 | Silkworm | Bombyx mori |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0943 | Dan Cai | 淡菜 | Mussel | Mytilus edulis |
| H0850 | Zi Su Ye | 紫苏叶 | Common perilla leaf | Perilla frutescens var. arguta |
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0393 | Sang Shen | 桑葚 | Mulberry | Morus alba |
| H0276 | Mu Zhao | 木爪 | Papayas | Carica papaya |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
Ckey description of the interaction between compound and target