Target Description

Type Detail
Target ID T13NLM
Protein Name Cell division control protein 42 homolog
Uniprot ID P60953
Protein Name Alias EC 3.6.5.2;  G25K GTP-binding protein
Gene ID 998
Gene Symbol CDC42
Gene Alias NA
TTD NA
Pfam PF00071
GO
0042059:negative regulation of epidermal growth factor receptor signaling pathway

0032991:protein-containing complex

0060501:positive regulation of epithelial cell proliferation involved in lung morphogenesis

0051835:positive regulation of synapse structural plasticity

0030031:cell projection assembly

0005925:focal adhesion

0071346:cellular response to interferon-gamma

0031435:mitogen-activated protein kinase kinase kinase binding

0034332:adherens junction organization

0046847:filopodium assembly

0060047:heart contraction

0072686:mitotic spindle

0035722:interleukin-12-mediated signaling pathway

0060661:submandibular salivary gland formation

0030742:GTP-dependent protein binding

0051492:regulation of stress fiber assembly

0017119:Golgi transport complex

0003161:cardiac conduction system development

0034613:cellular protein localization

0060071:Wnt signaling pathway, planar cell polarity pathway

0038189:neuropilin signaling pathway

0099563:modification of synaptic structure

0007097:nuclear migration

0051233:spindle midzone

0007229:integrin-mediated signaling pathway

0051056:regulation of small GTPase mediated signal transduction

0016477:cell migration

0043025:neuronal cell body

0031274:positive regulation of pseudopodium assembly

0007596:blood coagulation

0010592:positive regulation of lamellipodium assembly

0042802:identical protein binding

0030225:macrophage differentiation

0043552:positive regulation of phosphatidylinositol 3-kinase activity

0061630:ubiquitin protein ligase activity

0072384:organelle transport along microtubule

0046330:positive regulation of JNK cascade

1900026:positive regulation of substrate adhesion-dependent cell spreading

0031256:leading edge membrane

0032467:positive regulation of cytokinesis

0048664:neuron fate determination

0010591:regulation of lamellipodium assembly

0030175:filopodium

0034191:apolipoprotein A-I receptor binding

0031996:thioesterase binding

0051491:positive regulation of filopodium assembly

0090316:positive regulation of intracellular protein transport

0032488:Cdc42 protein signal transduction

0051149:positive regulation of muscle cell differentiation

0016020:membrane

0043197:dendritic spine

0045335:phagocytic vesicle

0030496:midbody

0045740:positive regulation of DNA replication

0090135:actin filament branching

2000251:positive regulation of actin cytoskeleton reorganization

0060997:dendritic spine morphogenesis

0099159:regulation of modification of postsynaptic structure

0051496:positive regulation of stress fiber assembly

0030307:positive regulation of cell growth

0048010:vascular endothelial growth factor receptor signaling pathway

0005886:plasma membrane

0043525:positive regulation of neuron apoptotic process

0007088:regulation of mitotic nuclear division

0019901:protein kinase binding

0034329:cell junction assembly

0007163:establishment or maintenance of cell polarity

0021762:substantia nigra development

0002040:sprouting angiogenesis

0070062:extracellular exosome

0006911:phagocytosis, engulfment

0005789:endoplasmic reticulum membrane

0038096:Fc-gamma receptor signaling pathway involved in phagocytosis

0031295:T cell costimulation

0030036:actin cytoskeleton organization

0005829:cytosol

0036464:cytoplasmic ribonucleoprotein granule

0051683:establishment of Golgi localization

0045177:apical part of cell

0098685:Schaffer collateral - CA1 synapse

0006897:endocytosis

0005911:cell-cell junction

0030141:secretory granule

0048549:positive regulation of pinocytosis

0039694:viral RNA genome replication

0005815:microtubule organizing center

0043005:neuron projection

0032427:GBD domain binding

0005737:cytoplasm

0000322:storage vacuole

0036336:dendritic cell migration

0045198:establishment of epithelial cell apical/basal polarity

0051988:regulation of attachment of spindle microtubules to kinetochore

0048013:ephrin receptor signaling pathway

0043393:regulation of protein binding

0051489:regulation of filopodium assembly

0031333:negative regulation of protein-containing complex assembly

0007015:actin filament organization

0005525:GTP binding

0000139:Golgi membrane

0007030:Golgi organization

0003924:GTPase activity

PDB 6SIU ; 4ITR ; 1AM4 ; 5HZK ; 2ASE ; 2WMO ; 6AJL ; 1AJE ; 5UPL ; 1CF4 ; 2DFK ; 6AJ4 ; 2WMN ; 4YC7 ; 3QBV ; 5FI1 ; 6TKY ; 4YDH ; 1AN0 ; 1DOA ; 2KB0 ; 4DID ; 5CJP ; 1NF3 ; 2ODB ; 2NGR ; 3GCG ; 4JS0 ; 1GZS ; 6TKZ ; 1EES ; 1KZG ; 2WM9 ; 1KZ7 ; 1GRN ; 1E0A ; 1CEE ; 1KI1 ; 6SUP ; 3VHL ; 2QRZ ; 5UPK ; 1A4R
Drugbank DB04315 ; DB02623
KEGG hsa:998

Related Compounds  (Total: 2)

Go to browser
C0363
Name: Resveratrol
Go to browser
C1138
Name: berberine


Related Herbs  (Total: 25)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0626 Xi Nan Huang Qin西南黄芩 Yunnan skullcapScutellaria amoena
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H0357 Ren Shen人参 GinsengPanax ginseng
H0883 Chuan She Gan川射干 BlackberrylilyBelamcanda chinensis
H0765 Chi Dou赤豆 Assuki beanVigna angularis
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H0472 Shu Da Huang熟大黄 NARheum palmatum
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0226 Man Yue Mei蔓越莓 CranberryVaccinium oxycoccos
H1166 He Shou Wu何首乌 Tuber fleeceflowerPolygonum multiflorum
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0617 Qian Cao Teng茜草藤 NARubia cordifolia
H1117 Guan Zhong贯众 Male fern rhizomeDryopteris crassirhizoma
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H0432 She Gan射干 BlackberrylilyBelamcanda chinensis
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0416 Shan Shen山参 NAPanax ginseng
H0434 She Pu Tao蛇葡萄 AmpelopsisAmpelopsis brevipedunculata
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba