Target Description

Type Detail
Target ID T32P8F
Protein Name Serine/threonine-protein phosphatase 5
Uniprot ID P53041
Protein Name Alias PP5;  EC 3.1.3.16;  Protein phosphatase T;  PP-T;  PPT
Gene ID 5536
Gene Symbol PPP5C
Gene Alias PPP5
TTD T04123: Patented target
Pfam PF00515 ; PF08321 ; PF00149
GO
0032991:protein-containing complex

0006470:protein dephosphorylation

0006351:transcription, DNA-templated

0000165:MAPK cascade

0043278:response to morphine

0005524:ATP binding

0001965:G-protein alpha-subunit binding

0070301:cellular response to hydrogen peroxide

0046872:metal ion binding

0005829:cytosol

0043531:ADP binding

0101031:chaperone complex

0042802:identical protein binding

0071276:cellular response to cadmium ion

0044877:protein-containing complex binding

0004722:protein serine/threonine phosphatase activity

2000324:positive regulation of glucocorticoid receptor signaling pathway

0005886:plasma membrane

0008289:lipid binding

0010288:response to lead ion

0005654:nucleoplasm

0043204:perikaryon

0106306:protein serine phosphatase activity

0000278:mitotic cell cycle

1901215:negative regulation of neuron death

0003723:RNA binding

0006302:double-strand break repair

0005634:nucleus

0070262:peptidyl-serine dephosphorylation

0035970:peptidyl-threonine dephosphorylation

1990635:proximal dendrite

0051879:Hsp90 protein binding

0016791:phosphatase activity

0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling

1904550:response to arachidonic acid

0008017:microtubule binding

0043231:intracellular membrane-bounded organelle

0106307:protein threonine phosphatase activity

0016576:histone dephosphorylation

0001933:negative regulation of protein phosphorylation

0048156:tau protein binding

0004721:phosphoprotein phosphatase activity

PDB 3H64 ; 1A17 ; 3H62 ; 4ZX2 ; 1S95 ; 5WG8 ; 2BUG ; 1WAO ; 3H63 ; 5HPE ; 3H68 ; 3H61 ; 3H69 ; 3H60 ; 3H66 ; 3H67 ; 5UI1 ; 4ZVZ
Drugbank DB00171
KEGG hsa:5536

Related Compounds  (Total: 2)

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C0055
Name: Estradiol
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C0917
Name: Arachidonic Acid


Related Herbs  (Total: 25)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0919 Cui Yun Cao翠云草 Hooked spikemossSelaginella uncinata
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H0461 Shi Jun Zi Ren使君子仁 NACombretum indicum
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0204 Ma Ren麻仁 NACannabis sativa
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0077 Jiu EthanolVinum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng