Target Description

Type Detail
Target ID T69ZRP
Protein Name Appetite-regulating hormone
Uniprot ID Q9UBU3
Protein Name Alias Growth hormone secretagogue;  Growth hormone-releasing peptide;  Motilin-related peptide;  Protein M46
Gene ID 51738
Gene Symbol GHRL
Gene Alias MTLRP
TTD T06850: Clinical Trial target
Pfam PF04644 ; PF04643
GO
0051464:positive regulation of cortisol secretion

0032095:regulation of response to food

0016525:negative regulation of angiogenesis

0043627:response to estrogen

0032024:positive regulation of insulin secretion

0030424:axon

0008343:adult feeding behavior

0120162:positive regulation of cold-induced thermogenesis

0007204:positive regulation of cytosolic calcium ion concentration

0098794:postsynapse

0060399:positive regulation of growth hormone receptor signaling pathway

0042127:regulation of cell population proliferation

0098978:glutamatergic synapse

0060124:positive regulation of growth hormone secretion

0040018:positive regulation of multicellular organism growth

0030296:protein tyrosine kinase activator activity

0046676:negative regulation of insulin secretion

0001696:gastric acid secretion

1903012:positive regulation of bone development

0040010:positive regulation of growth rate

1904346:positive regulation of gastric mucosal blood circulation

0001664:G protein-coupled receptor binding

0000187:activation of MAPK activity

0031768:ghrelin receptor binding

0046010:positive regulation of circadian sleep/wake cycle, non-REM sleep

0051216:cartilage development

1904000:positive regulation of eating behavior

0035774:positive regulation of insulin secretion involved in cellular response to glucose stimulus

0009755:hormone-mediated signaling pathway

1904349:positive regulation of small intestine smooth muscle contraction

0005615:extracellular space

1903672:positive regulation of sprouting angiogenesis

0001937:negative regulation of endothelial cell proliferation

0051965:positive regulation of synapse assembly

0099175:regulation of postsynapse organization

0051602:response to electrical stimulus

0046697:decidualization

0060079:excitatory postsynaptic potential

0035483:gastric emptying

0006006:glucose metabolic process

0098685:Schaffer collateral - CA1 synapse

0120058:positive regulation of small intestinal transit

1905333:regulation of gastric motility

0050728:negative regulation of inflammatory response

0051461:positive regulation of corticotropin secretion

0009725:response to hormone

0008154:actin polymerization or depolymerization

0032100:positive regulation of appetite

0043400:cortisol secretion

1904179:positive regulation of adipose tissue development

0051969:regulation of transmission of nerve impulse

0005576:extracellular region

0040013:negative regulation of locomotion

0032720:negative regulation of tumor necrosis factor production

1905564:positive regulation of vascular endothelial cell proliferation

0007186:G protein-coupled receptor signaling pathway

0099170:postsynaptic modulation of chemical synaptic transmission

0016358:dendrite development

0042322:negative regulation of circadian sleep/wake cycle, REM sleep

0034774:secretory granule lumen

0030252:growth hormone secretion

0032715:negative regulation of interleukin-6 production

0043066:negative regulation of apoptotic process

0032691:negative regulation of interleukin-1 beta production

0005788:endoplasmic reticulum lumen

0016608:growth hormone-releasing hormone activity

PDB 6H3E ; 1P7X
Drugbank NA
KEGG hsa:51738

Related Compounds  (Total: 2)

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C0247
Name: Nicotine
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C0436
Name: Testosterone


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H0847 Zi He Che紫河车 Human placentaHomo sapiens
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H0500 Can Yong蚕蛹 Silkworm chrysalisBombyx mori
H1204 Hu Jiao胡椒 Black pepperPiper nigrum