Target Description

Type Detail
Target ID T75F65
Protein Name Interleukin-2 receptor subunit alpha
Uniprot ID P01589
Protein Name Alias IL-2 receptor subunit alpha;  IL-2-RA;  IL-2R subunit alpha;  IL2-RA;  TAC antigen;  p55;  CD antigen CD25
Gene ID 3559
Gene Symbol IL2RA
Gene Alias NA
TTD T03313: Successful target
Pfam PF00084
GO
0042104:positive regulation of activated T cell proliferation

0000165:MAPK cascade

0006924:activation-induced cell death of T cells

0002437:inflammatory response to antigenic stimulus

0002664:regulation of T cell tolerance induction

0045582:positive regulation of T cell differentiation

0050777:negative regulation of immune response

0005893:interleukin-2 receptor complex

0045589:regulation of regulatory T cell differentiation

0007219:Notch signaling pathway

0046013:regulation of T cell homeostatic proliferation

0004911:interleukin-2 receptor activity

0007166:cell surface receptor signaling pathway

0019976:interleukin-2 binding

0006915:apoptotic process

0005886:plasma membrane

0009897:external side of plasma membrane

0042130:negative regulation of T cell proliferation

0050687:negative regulation of defense response to virus

0050728:negative regulation of inflammatory response

0006955:immune response

0019221:cytokine-mediated signaling pathway

0038110:interleukin-2-mediated signaling pathway

0006954:inflammatory response

PDB 6VWU ; 2B5I ; 3NFP ; 2ERJ ; 1Z92 ; 3IU3 ; 6YIO ; 1ILM ; 1ILN
Drugbank DB00004 ; DB00111 ; DB00074 ; DB00041
KEGG hsa:3559

Related Compounds  (Total: 4)

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C0739
Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione
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C1138
Name: berberine
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C1193
Name: Bisphenol A
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C1261
Name: Cpg


Related Herbs  (Total: 10)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0416 Shan Shen山参 NAPanax ginseng
H0357 Ren Shen人参 GinsengPanax ginseng
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens