| ID: C1193 | Common name: Bisphenol A |
| IUPAC: 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol | CAS: CAS:80-05-7 |
| Chembl ID: CHEMBL418971 | Pubchem ID: CID:6623 |
| Formula: C15H16O2 | TCM-ID: TCMC820 |
| Smiles: CC(c1ccc(cc1)O)(c1ccc(cc1)O)C | |
| Alias:
Phenol, 4,4'-isopropylidenedi-;
4,4'-(1-Methylethylidene)bis[phenol]; (4,4'-Dihydroxydiphenyl)dimethylmethane; 2,2-Bis(4-hydroxyphenyl)propane; 2,2-Bis(p-hydroxyphenyl)propane; 2,2-Di(4-hydroxyphenyl)propane; 2,2-Di(4-phenylol)propane; 2,2'-Bis(4-hydroxyphenyl)propane; 4,4'-(Propane-2,2-diyl)diphenol; 4,4'-Isopropylidenebis[phenol]; 4,4'-Isopropylidenediphenol; 4,4'-Methylethylidenebisphenol; B 0494; BPA; BPA 154; BPA 157; BPA-M; Bis(4-hydroxyphenyl)dimethylmethane; Bis(p-hydroxyphenyl)propane; Bisphenol A; Dian; Diano; Diphenylolpropane; HT 3082; Hidorin F 285; Hidorin F 568; Ipognox 88; Isopropylidenebis(4-hydroxybenzene); NSC 1767; NSC 17959; Parabis; Parabis A; Pluracol 245; Rikabanol; p,p'-Bisphenol A; p,p'-Dihydroxydiphenylpropane; p,p'-Isopropylidenebisphenol; p,p'-Isopropylidenediphenol; β,β'-Bis(p-hydroxyphenyl)propane |
Structure:
|
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
A | 4 Reference(s) |
| T92E71 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | HSD11B2 |
P80365 |
A | 1 Reference(s) |
| T82S6C | Hexokinase-4 | GCK |
P35557 |
A | 1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
A | 2 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
A | 1 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
A | 1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
A | 10 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
A | 1 Reference(s) |
| T77TY2 | Protein disulfide-isomerase | P4HB |
P07237 |
A | 2 Reference(s) |
| T51MEE | Testosterone 17-beta-dehydrogenase 3 | HSD17B3 |
P37058 |
A | 1 Reference(s) |
| T76HDG | Lymphatic vessel endothelial hyaluronic acid receptor 1 | LYVE1 |
Q9Y5Y7 |
A | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
A | 1 Reference(s) |
| T30KQB | Alanine aminotransferase 1 | GPT |
P24298 |
A | 1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
A | 2 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
A | 4 Reference(s) |
| T52NOH | Estrogen-related receptor gamma | ESRRG |
P62508 |
A | 3 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
A | 1 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
B | 2 Reference(s) |
| T32YAJ | G-protein coupled estrogen receptor 1 | GPER1 |
Q99527 |
B | 3 Reference(s) |
| T57YL7 | Sex hormone-binding globulin | SHBG |
P04278 |
B | 1 Reference(s) |
| T47G3X | Glucocorticoid receptor | NR3C1 |
P04150 |
B | 2 Reference(s) |
| T18YXD | Albumin | ALB |
P02768 |
B | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
B | 1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
B | 2 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
B | 2 Reference(s) |
| T55TEP | Steroidogenic acute regulatory protein, mitochondrial | STAR |
P49675 |
B | 1 Reference(s) |
| T80R6A | Insulin-like growth factor I | IGF1 |
P05019 |
C | 1 Reference(s) |
| T53SLQ | Aquaporin-9 | AQP9 |
O43315 |
C | 1 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
C | 2 Reference(s) |
| T15VAS | Integrin beta-1 | ITGB1 |
P05556 |
C | 1 Reference(s) |
| T09KQF | Proliferating cell nuclear antigen | PCNA |
P12004 |
C | 1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
C | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 3 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
C | 1 Reference(s) |
| T30VLU | Agouti-related protein | AGRP |
O00253 |
C | 1 Reference(s) |
| T96HZ7 | Retinoic acid receptor responder protein 2 | RARRES2 |
Q99969 |
C | 2 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
| T53IT9 | Paired box protein Pax-6 | PAX6 |
P26367 |
C | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
C | 2 Reference(s) |
| T30VA7 | Stromelysin-3 | MMP11 |
P24347 |
C | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
| T63RJO | Growth arrest and DNA damage-inducible protein GADD45 beta | GADD45B |
O75293 |
C | 1 Reference(s) |
| T98QOA | DNA-dependent protein kinase catalytic subunit | PRKDC |
P78527 |
C | 1 Reference(s) |
| T05WWN | Corticoliberin | CRH |
P06850 |
C | 1 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
C | 1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
C | 2 Reference(s) |
| T75F65 | Interleukin-2 receptor subunit alpha | IL2RA |
P01589 |
C | 1 Reference(s) |
| T51RTI | NA | HOTAIR |
NA |
C | 1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
C | 1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
C | 1 Reference(s) |
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
C | 1 Reference(s) |
| T11HTL | Apelin | APLN |
Q9ULZ1 |
C | 1 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
C | 1 Reference(s) |
| T37SV3 | Occludin | OCLN |
Q16625 |
C | 1 Reference(s) |
| T18DUA | Tight junction protein ZO-1 | TJP1 |
Q07157 |
C | 1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
C | 1 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
C | 1 Reference(s) |