Compound Description

ID:   C1193 Common name:   Bisphenol A
IUPAC:  4-[2-(4-hydroxyphenyl)propan-2-yl]phenol CAS:  CAS:80-05-7
Chembl ID:   CHEMBL418971 Pubchem ID:   CID:6623
Formula:  C15H16O2 TCM-ID:  TCMC820
Smiles:  CC(c1ccc(cc1)O)(c1ccc(cc1)O)C
Alias:

Phenol, 4,4'-isopropylidenedi-;

4,4'-(1-Methylethylidene)bis[phenol];

(4,4'-Dihydroxydiphenyl)dimethylmethane;

2,2-Bis(4-hydroxyphenyl)propane;

2,2-Bis(p-hydroxyphenyl)propane;

2,2-Di(4-hydroxyphenyl)propane;

2,2-Di(4-phenylol)propane;

2,2'-Bis(4-hydroxyphenyl)propane;

4,4'-(Propane-2,2-diyl)diphenol;

4,4'-Isopropylidenebis[phenol];

4,4'-Isopropylidenediphenol;

4,4'-Methylethylidenebisphenol;

B 0494;

BPA;

BPA 154;

BPA 157;

BPA-M;

Bis(4-hydroxyphenyl)dimethylmethane;

Bis(p-hydroxyphenyl)propane;

Bisphenol A;

Dian;

Diano;

Diphenylolpropane;

HT 3082;

Hidorin F 285;

Hidorin F 568;

Ipognox 88;

Isopropylidenebis(4-hydroxybenzene);

NSC 1767;

NSC 17959;

Parabis;

Parabis A;

Pluracol 245;

Rikabanol;

p,p'-Bisphenol A;

p,p'-Dihydroxydiphenylpropane;

p,p'-Isopropylidenebisphenol;

p,p'-Isopropylidenediphenol;

β,β'-Bis(p-hydroxyphenyl)propane
Structure:

Related Targets  (Total: 59)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T50SX0 Nuclear receptor subfamily 1 group I member 2NR1I2 O75469
A 4 Reference(s)
T92E71 Corticosteroid 11-beta-dehydrogenase isozyme 2HSD11B2 P80365
A 1 Reference(s)
T82S6C Hexokinase-4GCK P35557
A 1 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
A 2 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
A 1 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
A 1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
A 10 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
A 1 Reference(s)
T77TY2 Protein disulfide-isomeraseP4HB P07237
A 2 Reference(s)
T51MEE Testosterone 17-beta-dehydrogenase 3HSD17B3 P37058
A 1 Reference(s)
T76HDG Lymphatic vessel endothelial hyaluronic acid receptor 1LYVE1 Q9Y5Y7
A 1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
A 1 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
A 1 Reference(s)
T30KQB Alanine aminotransferase 1GPT P24298
A 1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
A 2 Reference(s)
T05O6O Estrogen receptor betaESR2 Q92731
A 4 Reference(s)
T52NOH Estrogen-related receptor gammaESRRG P62508
A 3 Reference(s)
T40DIM Corticosteroid 11-beta-dehydrogenase isozyme 1HSD11B1 P28845
A 1 Reference(s)
T84W8G Aryl hydrocarbon receptorAHR P35869
B 2 Reference(s)
T32YAJ G-protein coupled estrogen receptor 1GPER1 Q99527
B 3 Reference(s)
T57YL7 Sex hormone-binding globulinSHBG P04278
B 1 Reference(s)
T47G3X Glucocorticoid receptorNR3C1 P04150
B 2 Reference(s)
T18YXD AlbuminALB P02768
B 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
B 1 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
B 1 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
B 2 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
B 2 Reference(s)
T55TEP Steroidogenic acute regulatory protein, mitochondrialSTAR P49675
B 1 Reference(s)
T80R6A Insulin-like growth factor IIGF1 P05019
C 1 Reference(s)
T53SLQ Aquaporin-9AQP9 O43315
C 1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
C 2 Reference(s)
T15VAS Integrin beta-1ITGB1 P05556
C 1 Reference(s)
T09KQF Proliferating cell nuclear antigenPCNA P12004
C 1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
C 1 Reference(s)
T33OPP Interleukin-6IL6 P05231
C 3 Reference(s)
T16A2X CatalaseCAT P04040
C 1 Reference(s)
T30VLU Agouti-related proteinAGRP O00253
C 1 Reference(s)
T96HZ7 Retinoic acid receptor responder protein 2RARRES2 Q99969
C 2 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
C 1 Reference(s)
T53IT9 Paired box protein Pax-6PAX6 P26367
C 1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
C 2 Reference(s)
T30VA7 Stromelysin-3MMP11 P24347
C 1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
C 1 Reference(s)
T63RJO Growth arrest and DNA damage-inducible protein GADD45 betaGADD45B O75293
C 1 Reference(s)
T98QOA DNA-dependent protein kinase catalytic subunitPRKDC P78527
C 1 Reference(s)
T05WWN CorticoliberinCRH P06850
C 1 Reference(s)
T53YWQ Pro-neuropeptide Y [Cleaved into: Neuropeptide YNPY P01303
C 1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
C 2 Reference(s)
T75F65 Interleukin-2 receptor subunit alphaIL2RA P01589
C 1 Reference(s)
T51RTI NAHOTAIR NA
C 1 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
C 1 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
C 1 Reference(s)
T88LSZ AromataseCYP19A1 P11511
C 1 Reference(s)
T11HTL ApelinAPLN Q9ULZ1
C 1 Reference(s)
T76TED Pro-opiomelanocortinPOMC P01189
C 1 Reference(s)
T37SV3 OccludinOCLN Q16625
C 1 Reference(s)
T18DUA Tight junction protein ZO-1TJP1 Q07157
C 1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
C 1 Reference(s)
T20JZ2 Androgen receptorAR P10275
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0416 Shan Shen山参 NAPanax ginseng
H0357 Ren Shen人参 GinsengPanax ginseng
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens