HIT-result

Type	Detail
Target ID	T77A47
Protein Name	Eukaryotic translation initiation factor 4E
Uniprot ID	P06730
Protein Name Alias	eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Gene ID	1977
Gene Symbol	EIF4E
Gene Alias	EIF4EL1; EIF4F
TTD	T31186: Research target
Pfam	PF01652
GO	0005634:nucleus 0001662:behavioral fear response 0071549:cellular response to dexamethasone stimulus 0017148:negative regulation of translation 0005829:cytosol 0070491:repressing transcription factor binding 0030324:lung development 0099578:regulation of translation at postsynapse, modulating synaptic transmission 0010494:cytoplasmic stress granule 0005845:mRNA cap binding complex 0098978:glutamatergic synapse 0019899:enzyme binding 0006405:RNA export from nucleus 0000339:RNA cap binding 0070062:extracellular exosome 0019827:stem cell population maintenance 0033391:chromatoid body 0036464:cytoplasmic ribonucleoprotein granule 0016281:eukaryotic translation initiation factor 4F complex 0006406:mRNA export from nucleus 0003743:translation initiation factor activity 0000082:G1/S transition of mitotic cell cycle 0031370:eukaryotic initiation factor 4G binding 0000932:P-body 0006413:translational initiation 0045665:negative regulation of neuron differentiation 0045931:positive regulation of mitotic cell cycle 0016442:RISC complex 0006417:regulation of translation 0005737:cytoplasm 0000340:RNA 7-methylguanosine cap binding 0099524:postsynaptic cytosol 0048471:perinuclear region of cytoplasm 0003723:RNA binding 0016032:viral process
PDB	1WKW ; 3AM7 ; 3TF2 ; 5ZK7 ; 5ZML ; 4AZA ; 2V8Y ; 5T46 ; 5EIR ; 5ZJY ; 5ZK9 ; 4BEA ; 5EKV ; 4TQB ; 4UED ; 5ZK5 ; 4DT6 ; 2V8W ; 2W97 ; 4DUM ; 5EHC ; 4TQC ; 5EI3 ; 5GW6 ; 5ZJZ ; 2GPQ ; 3U7X ; 4TPW ; 1IPB ; 2V8X ; 1IPC
Drugbank	DB08217 ; DB01960 ; DB02716 ; DB05165 ; DB01649
KEGG	hsa:1977

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Name: Delphinidin

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Name: Metformin

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Name: Paclitaxel

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Name: Α-Elemene,Β-Elemene

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Name: cortisone

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0670	Chai Pi Zhang	豺皮樟	Oblong-leaved litsea	Litsea rotundifolia
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H0430	She Chuang Zi	蛇床子	Common cnidium	Cnidium monnieri
H0060	Jin Si Ku Lian	金丝苦楝	NA	Cardiospermum halicacabum
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0464	Shi Liu Zi	石榴子	NA	Punica granatum
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens