Compound Description
| ID: C0532 | Common name: Procyanidin B2 |
| IUPAC: (2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol | CAS: CAS:29106-49-8 |
| Chembl ID: CHEMBL38714 | Pubchem ID: CID:122738 |
| Formula: C30H26O12 | TCM-ID: TCMC2580 |
| Smiles: C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O | |
| Alias:
[4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-, [2R-[2α,3α,4β(2'R*,3'R*)]]-;
[4,8''-Biflavan]-3,3',3'',3''',4',4''',5,5'',7,7''-decol, stereoisomer; (2R,2'R,3R,3'R,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro[4,8'-bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol; (+)-Procyanidin B2; (-)-Epicatechin-(4β→8)-(-)-epicatechin; Proanthocyanidin B2; Procyanidin B2; Procyanidol B2 |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T25UYT | Dual specificity mitogen-activated protein kinase kinase 4 | MAP2K4 |
P45985 |
A | 1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
A | 1 Reference(s) |
| T75IW3 | Matrix metalloproteinase-14 | MMP14 |
P50281 |
A | 1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
C | 1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
C | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 40)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0786 | Zhang Mu | 樟木 | Ligum cinmamomi camphorae | Cinnamomum camphora |
| H1139 | Gui Zhi | 桂枝 | Cassiabarktree twig | Cinnamomum cassia |
| H0789 | Zhang Shu Gen | 樟树根 | Camphor tree | Cinnamomum camphora |
| H0967 | Di Er Cao | 地耳草 | Japanese stJohn’swort | Hypericum japonicum |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0366 | Rou Gui | 肉桂 | Cassiabarktree | Cinnamomum cassia |
| H0787 | Zhang Nao | 樟脑 | Camphorar | Cinnamomum camphora |
| H0615 | Wu Zhi Mao Tao | 五指毛桃 | five-finger fig root | Ficus simplicissima |
| H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0408 | Bing Lang | 槟榔 | Betenutpalm | Areca catechu |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H1212 | Hu Ye Gan Jin Gao | 槲叶干浸膏 | NA | Quercus dentata |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0925 | Da Fu Zi | 大腹子 | Areca palm | Areca catechu |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
| H0790 | Zhang Shu Zi | 樟树子 | Camphor tree | Cinnamomum camphora |
| H1114 | Guan Gui | 官桂 | Cassiabarktree | Cinnamomum cassia |
| H0478 | Shu Lang | 薯莨 | NA | Dioscorea cirrhosa |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H1137 | Gui Yuan | 桂圆 | NA | Dimocarpus longan |
| H0308 | Pi Ba Ren | 枇杷仁 | NA | Eriobotrya japonica |
| H0368 | Rou Gui Zi | 肉桂子 | Cassiabarktree | Cinnamomum cassia |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0056 | Jin Qiao Mai | 金荞麦 | Wild buckwheat rhizome | Rhizoma fagopyri cymosi |
| H0764 | Yu Xing Cao | 鱼腥草 | Heartleaf houttuynia | Houttuynia cordata |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0788 | Zhang Nao Zi | 樟脑子 | Camphorar | Cinnamomum camphora |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
Ckey description of the interaction between compound and target