Compound Description
| ID: C0540 | Common name: Cis-Asarone |
| IUPAC: 1,2,4-trimethoxy-5-[(Z)-prop-1-enyl]benzene | CAS: CAS:5273-86-9 |
| Chembl ID: CHEMBL477752 | Pubchem ID: CID:5281758 |
| Formula: C12H16O3 | TCM-ID: TCMC2688 |
| Smiles: CC=CC1=CC(=C(C=C1OC)OC)OC | |
| Alias:
Benzene, 1,2,4-trimethoxy-5-(1-propenyl)-, (Z)-;
Benzene, 1,2,4-trimethoxy-5-(1Z)-1-propenyl-; Benzene, 1,2,4-trimethoxy-5-propenyl-, (Z)-; β-Asarone; 1,2,4-Trimethoxy-5-(1Z)-1-propen-1-ylbenzene; (Z)-Asarone; (Z)-Azarone; cis-Asarone; cis-Isoasarone; cis-β-Asarone |
Structure:
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Related Targets (Total: 14)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T92FAW | Dual specificity protein phosphatase 1 | DUSP1 |
P28562 |
A | 1 Reference(s) |
| T57RCH | Glutamate decarboxylase 2 | GAD2 |
Q05329 |
C | 1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
C | 1 Reference(s) |
| T40JZG | GPI-anchor transamidase | PIGK |
Q92643 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 2 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
C | 2 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
C | 2 Reference(s) |
| T58CAO | Alpha-synuclein | SNCA |
P37840 |
C | 1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
C | 1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
C | 1 Reference(s) |
| T57FUN | Beclin-1 | BECN1 |
Q14457 |
C | 1 Reference(s) |
| T95EK6 | Microtubule-associated proteins 1A/1B light chain 3B | MAP1LC3B |
Q9GZQ8 |
C | 1 Reference(s) |
| T67HXL | Glial cell line-derived neurotrophic factor | GDNF |
P39905 |
C | 1 Reference(s) |
| T91IWA | Ciliary neurotrophic factor | CNTF |
P26441 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 21)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1165 | He Shi | 鹤虱 | Common carpesium fruit | Fructus carpesii |
| H0769 | Yuan Zhi | 远志 | Thinleaf milkwort | Polygala tenuifolia |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0699 | Chang Pu | 菖蒲 | rhizome of grassleaf sweetflag. | Acorus calamus |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0452 | Shi Chang Pu Qing Gao | 石菖蒲清膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1090 | Gao Ben | 藁本 | Chinese ligusticum | Ligusticum sinense |
| H0483 | Shui Chang Pu | 水菖蒲 | Calamus | Acorus calamus var. angustatus |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0450 | Shi Chang Pu | 石菖蒲 | Grassleaved sweetflag | Acorus tatarinowii |
| H0164 | Ban Zhi Lian | 半枝莲 | Barbed skullcap | Scutellaria barbata |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0505 | Cang Chang Pu | 藏菖蒲 | Sweet flag | Acorus calamus |
| H0771 | Yuan Zhi Liu Jin Gao | 远志流浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H0770 | Yuan Zhi Jin Gao | 远志浸膏 | Thinleaf milkwort | Polygala tenuifolia |
| H0451 | Shi Chang Pu Jin Gao | 石菖蒲浸膏 | Grassleaved sweetflag | Acorus tatarinowii |
Ckey description of the interaction between compound and target