Compound Description

ID:   C0040 Common name:   Embelin
IUPAC:  2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione CAS:  CAS:550-24-3
Chembl ID:   CHEMBL221137 Pubchem ID:   CID:3218
Formula:  C17H26O4 TCM-ID:  TCMC1104
Smiles:  CCCCCCCCCCCC1=C(O)C(=O)C=C(C1=O)O
Alias:

Embelin;

p-Benzoquinone, 2,5-dihydroxy-3-undecyl-;

2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione;

2,5-Dihydroxy-3-undecyl-1,4-benzoquinone;

2,5-Dihydroxy-3-undecylcyclohexa-2,5-dien-1,4-dione;

Embelic acid;

Emberine;

NSC 91874
Structure:

Related Targets  (Total: 15)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T14LSK E3 ubiquitin-protein ligase XIAPXIAP P98170
A 12 Reference(s)
T56TXY Polyunsaturated fatty acid 5-lipoxygenaseALOX5 P09917
A 1 Reference(s)
T47HTN Prostaglandin E synthasePTGES O14684
A 2 Reference(s)
T91MWA Disintegrin and metalloproteinase domain-containing protein 17ADAM17 P78536
A 1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
A 2 Reference(s)
T95K8Q Intestinal-type alkaline phosphataseALPI P09923
A 1 Reference(s)
T31M1Q NeuroserpinSERPINI1 Q99574
B 1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
B 1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
C 1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
C 1 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
C 1 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
C 1 Reference(s)
T08OEP Monocyte differentiation antigen CD14CD14 P08571
C 1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
C 1 Reference(s)
T32IXS Integrin alpha-MITGAM P11215
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1011 Bai Chou白丑 Pharbitis seedSemen pharbitidis
H1173 Hei Chou黑丑 Pharbitis seedSemen pharbitidis
H0592 Wei Ling Xian威灵仙 Chinese clematisClematis chinensis
H0329 Qian Niu Zi牵牛子 Lobedleaf pharbitis seedPharbitis nil
H0848 Zi Jin Niu紫金牛 Japanese ardisiaArdisia japonica
H0590 Wei Ling威灵 Chinese clematisClematis chinensis
H0832 Zhu Sha Gen朱砂根 Coral ardisiaArdisia crenata