Compound Description

ID:   C0283 Common name:   Paeonol
IUPAC:  1-(2-hydroxy-4-methoxyphenyl)ethanone CAS:  CAS:552-41-0
Chembl ID:   CHEMBL1079227 Pubchem ID:   CID:11092
Formula:  C9H10O3 TCM-ID:  TCMC1826
Smiles:  CC(=O)C1=C(C=C(C=C1)OC)O
Alias:

Acetophenone, 2'-hydroxy-4'-methoxy-;

Peonol;

1-(2-Hydroxy-4-methoxyphenyl)ethanone;

1-(2-Hydroxy-4-methoxyphenyl)ethan-1-one;

1-(4-Methoxy-2-hydroxyphenyl)ethanone;

2-Acetyl-5-methoxyphenol;

2-Hydroxy-4-methoxyphenyl methyl ketone;

2'-Hydroxy-4'-methoxyacetophenone;

4-Methoxy-2-hydroxyacetophenone;

4-O-Methylresacetophenone;

4'-Methoxy-2'-hydroxyacetophenone;

NSC 401442;

Paconol;

Paeonol;

Paeonolum;

Resacetophenone 4-O-methyl ether
Structure:

Related Targets  (Total: 21)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T34DZ7 Interleukin-2IL2 P60568
A 1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
A 1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
A 1 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
A 1 Reference(s)
T38N69 Lymphokine-activated killer T-cell-originated protein kinasePBK Q96KB5
A 1 Reference(s)
T09BRP NAPKB_RS07820 NA
A 1 Reference(s)
T83P5X Inhibitor of nuclear factor kappa-B kinase subunit betaIKBKB O14920
A 1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
A 1 Reference(s)
T74LFK Neurogenic locus notch homolog protein 1NOTCH1 P46531
A 1 Reference(s)
T06Q1R Amine oxidase [flavin-containing] BMAOB P27338
B 1 Reference(s)
T44LWL Transcription factor p65RELA Q04206
B 2 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
B 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
B 1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
B 1 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
B 1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
B 1 Reference(s)
T13KGH TyrosinaseTYR P14679
B 1 Reference(s)
T75PC7 NAMIR21 NA
B 1 Reference(s)
T66G0O NAMIR30A NA
B 1 Reference(s)
T67ZT3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENPTEN P60484
C 1 Reference(s)
T21UJU Troponin I, cardiac muscleTNNI3 P19429
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 35)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0238 Mei Hua梅花 Plum flowerFlos mume
H0416 Shan Shen山参 NAPanax ginseng
H0629 Xi Xin细辛 Siebold wildgingerAsarum sieboldii
H0338 Qing Ban Xia清半夏 Ternate pinelliaPinellia ternata
H0155 Ban Xia半夏 Ternate pinelliaPinellia ternata
H0159 Ban Xia Qu半夏曲 Pinellia tuber leavenPinellia ternata
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0642 Xiang Jia Pi香加皮 Chinese silkvine root-barkPeriploca sepium
H0673 Xin Jiang Zi Cao新疆紫草 Arnebia rootArnebia euchroma
H0204 Ma Ren麻仁 NACannabis sativa
H1188 Hong Hua红花 SafflowerCarthamus tinctorius
H0968 Di Feng Pi地枫皮 Difengpi anisetreeIllicium difengpi
H1162 Hang Shao杭芍 White peony rootPaeonia albiflora
H0684 Xu Chang Qing徐长卿 Paniculate swallowwortCynanchum paniculatum
H0429 Shao Yao芍药 Red peony rootPaeonia obovata
H0452 Shi Chang Pu Qing Gao石菖蒲清膏 Grassleaved sweetflagAcorus tatarinowii
H0784 Chi Shao赤芍 Red peony rootPaeonia obovata
H0273 Mu Tong木通 Fiveleaf akebiaAkebia quinata
H0023 Bai Shao Gan Jin Gao白芍干浸膏 Common peonyPaeonia lactiflora
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0439 Sheng Ban Xia生半夏 Ternate pinelliaPinellia ternata
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H1036 Fen Dan Pi粉丹皮 Tree peony barkPaeonia suffruticosa
H0021 Bai Shao白芍 Common peonyPaeonia lactiflora
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0450 Shi Chang Pu石菖蒲 Grassleaved sweetflagAcorus tatarinowii
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0266 Mu Dan Pi牡丹皮 Subshrubby peony barkPaeonia moutan
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H0071 Bai Ye柏叶 Chinese arborvitae twigPlatycladus orientalis
H0357 Ren Shen人参 GinsengPanax ginseng
H0451 Shi Chang Pu Jin Gao石菖蒲浸膏 Grassleaved sweetflagAcorus tatarinowii