Compound Description
| ID: C0283 | Common name: Paeonol |
| IUPAC: 1-(2-hydroxy-4-methoxyphenyl)ethanone | CAS: CAS:552-41-0 |
| Chembl ID: CHEMBL1079227 | Pubchem ID: CID:11092 |
| Formula: C9H10O3 | TCM-ID: TCMC1826 |
| Smiles: CC(=O)C1=C(C=C(C=C1)OC)O | |
| Alias:
Acetophenone, 2'-hydroxy-4'-methoxy-;
Peonol; 1-(2-Hydroxy-4-methoxyphenyl)ethanone; 1-(2-Hydroxy-4-methoxyphenyl)ethan-1-one; 1-(4-Methoxy-2-hydroxyphenyl)ethanone; 2-Acetyl-5-methoxyphenol; 2-Hydroxy-4-methoxyphenyl methyl ketone; 2'-Hydroxy-4'-methoxyacetophenone; 4-Methoxy-2-hydroxyacetophenone; 4-O-Methylresacetophenone; 4'-Methoxy-2'-hydroxyacetophenone; NSC 401442; Paconol; Paeonol; Paeonolum; Resacetophenone 4-O-methyl ether |
Structure:
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Related Targets (Total: 21)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
A | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
A | 1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
A | 1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
A | 1 Reference(s) |
| T38N69 | Lymphokine-activated killer T-cell-originated protein kinase | PBK |
Q96KB5 |
A | 1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
A | 1 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
A | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
A | 1 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
A | 1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
B | 1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
B | 2 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
B | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
B | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
B | 1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
B | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
B | 1 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
B | 1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
B | 1 Reference(s) |
| T66G0O | NA | MIR30A |
NA |
B | 1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
C | 1 Reference(s) |
| T21UJU | Troponin I, cardiac muscle | TNNI3 |
P19429 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 35)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0452 | Shi Chang Pu Qing Gao | 石菖蒲清膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H0023 | Bai Shao Gan Jin Gao | 白芍干浸膏 | Common peony | Paeonia lactiflora |
| H0673 | Xin Jiang Zi Cao | 新疆紫草 | Arnebia root | Arnebia euchroma |
| H0784 | Chi Shao | 赤芍 | Red peony root | Paeonia obovata |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H1036 | Fen Dan Pi | 粉丹皮 | Tree peony bark | Paeonia suffruticosa |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0204 | Ma Ren | 麻仁 | NA | Cannabis sativa |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H0003 | Huo Ma Ren | 火麻仁 | Hemp fimble seed | Cannabis sativa |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0451 | Shi Chang Pu Jin Gao | 石菖蒲浸膏 | Grassleaved sweetflag | Acorus tatarinowii |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |
| H0273 | Mu Tong | 木通 | Fiveleaf akebia | Akebia quinata |
| H0629 | Xi Xin | 细辛 | Siebold wildginger | Asarum sieboldii |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H0071 | Bai Ye | 柏叶 | Chinese arborvitae twig | Platycladus orientalis |
| H0844 | Zi Cao | 紫草 | Redroot gromwell | Lithospermum erythrorhizon |
| H0266 | Mu Dan Pi | 牡丹皮 | Subshrubby peony bark | Paeonia moutan |
| H0642 | Xiang Jia Pi | 香加皮 | Chinese silkvine root-bark | Periploca sepium |
| H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H0968 | Di Feng Pi | 地枫皮 | Difengpi anisetree | Illicium difengpi |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0450 | Shi Chang Pu | 石菖蒲 | Grassleaved sweetflag | Acorus tatarinowii |
| H0429 | Shao Yao | 芍药 | Red peony root | Paeonia obovata |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0021 | Bai Shao | 白芍 | Common peony | Paeonia lactiflora |
| H1162 | Hang Shao | 杭芍 | White peony root | Paeonia albiflora |
| H0684 | Xu Chang Qing | 徐长卿 | Paniculate swallowwort | Cynanchum paniculatum |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0238 | Mei Hua | 梅花 | Plum flower | Flos mume |
Ckey description of the interaction between compound and target