Herb ID: H0542 | Chinese Character: 天麻 |
English Name: Tall gastrodia | Latin Name: Gastrodia elata |
Chinese Pin Yin : Tian Ma | TCM-ID: TCMH2090 |
Therapeutic Function in Chinese : 平肝息风 | Therapeutic Function in English: For calming liver and containing wind |
Herb Function: Subdue the liver-wind and arrest convulsions |
Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
---|---|---|---|---|
T70KPE | Transient receptor potential cation channel subfamily V member 3 | TRPV3 |
Q8NET8 |
1 Reference(s) |
T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
2 Reference(s) |
T98QOA | DNA-dependent protein kinase catalytic subunit | PRKDC |
P78527 |
2 Reference(s) |
T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
4 Reference(s) |
T31EJG | Apoptotic protease-activating factor 1 | APAF1 |
O14727 |
1 Reference(s) |
T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
1 Reference(s) |
T35QZO | Cytochrome c | CYCS |
P99999 |
1 Reference(s) |
T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
4 Reference(s) |
T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
T31MUM | 5,6-dihydroxyindole-2-carboxylic acid oxidase | TYRP1 |
P17643 |
1 Reference(s) |
T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
1 Reference(s) |
T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
T38N54 | Fumarate hydratase, mitochondrial | FH |
P07954 |
1 Reference(s) |
T18VDI | Apoptosis-inducing factor 1, mitochondrial | AIFM1 |
O95831 |
1 Reference(s) |
T62KUY | Endonuclease G, mitochondrial | ENDOG |
Q14249 |
1 Reference(s) |
T90ADC | BH3-interacting domain death agonist | BID |
P55957 |
1 Reference(s) |
T00T99 | S-adenosylhomocysteine hydrolase-like protein 1 | AHCYL1 |
O43865 |
1 Reference(s) |
T21CMG | Hepcidin | HAMP |
P81172 |
2 Reference(s) |
T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
3 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
11 Reference(s) |
T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
T01QLH | Estrogen receptor | ESR1 |
P03372 |
1 Reference(s) |
T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
1 Reference(s) |
T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
1 Reference(s) |
T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
1 Reference(s) |
T54VET | Protein tyrosine phosphatase type IVA 3 | PTP4A3 |
O75365 |
2 Reference(s) |
T11ZYR | Cytochrome P450 2D6 | CYP2D6 |
P10635 |
1 Reference(s) |
T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
4 Reference(s) |
T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
T37BP1 | Serine/threonine-protein kinase pim-1 | PIM1 |
P11309 |
1 Reference(s) |
T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
2 Reference(s) |
T20VPX | Cyclin-dependent-like kinase 5 | CDK5 |
Q00535 |
1 Reference(s) |
T00RT4 | Inosine-5'-monophosphate dehydrogenase 1 | IMPDH1 |
P20839 |
1 Reference(s) |
T68B5V | Inosine-5'-monophosphate dehydrogenase 2 | IMPDH2 |
P12268 |
1 Reference(s) |
T78C6N | Cathepsin K | CTSK |
P43235 |
1 Reference(s) |
T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
1 Reference(s) |
T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
1 Reference(s) |
T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
1 Reference(s) |
T25RTY | C-C motif chemokine 22 | CCL22 |
O00626 |
1 Reference(s) |
T77O2V | Mannose-1-phosphate guanyltransferase beta | GMPPB |
Q9Y5P6 |
1 Reference(s) |
T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
T22H8P | Carbonic anhydrase 3 | CA3 |
P07451 |
1 Reference(s) |
T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
T05V67 | Toll-like receptor 8 | TLR8 |
Q9NR97 |
1 Reference(s) |
T38T1U | Caspase-8 | CASP8 |
Q14790 |
3 Reference(s) |
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
3 Reference(s) |
T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
T88LSZ | Aromatase | CYP19A1 |
P11511 |
1 Reference(s) |
T48TW0 | Platelet glycoprotein 4 | CD36 |
P16671 |
1 Reference(s) |
T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
1 Reference(s) |
T99XQ3 | DNA topoisomerase 1 | TOP1 |
P11387 |
1 Reference(s) |
T33OPP | Interleukin-6 | IL6 |
P05231 |
1 Reference(s) |
T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
T36NQ9 | Mothers against decapentaplegic homolog 1 | SMAD1 |
Q15797 |
2 Reference(s) |
T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
1 Reference(s) |
T22J9V | Tyrosine-protein kinase JAK1 | JAK1 |
P23458 |
1 Reference(s) |
T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
1 Reference(s) |
T68CKY | Tyrosine-protein kinase Fyn | FYN |
P06241 |
1 Reference(s) |
T37WY2 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | PCK1 |
P35558 |
1 Reference(s) |
T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
2 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
4 Reference(s) |
T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
T68AKE | Zinc fingers and homeoboxes protein 2 | ZHX2 |
Q9Y6X8 |
1 Reference(s) |
T14DX3 | Ribosomal protein S6 kinase alpha-3 | RPS6KA3 |
P51812 |
1 Reference(s) |
T01HJQ | Calreticulin | CALR |
P27797 |
1 Reference(s) |
T86J48 | Sodium/glucose cotransporter 1 | SLC5A1 |
P13866 |
2 Reference(s) |
T02WMA | Ornithine decarboxylase | ODC1 |
P11926 |
1 Reference(s) |
T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
T16A2X | Catalase | CAT |
P04040 |
1 Reference(s) |
T71B0A | Cytosolic phospholipase A2 | PLA2G4A |
P47712 |
1 Reference(s) |
T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
1 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
T76AZQ | Histidine decarboxylase | HDC |
P19113 |
1 Reference(s) |
T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
3 Reference(s) |
T41BYM | Fibroblast growth factor 23 | FGF23 |
Q9GZV9 |
1 Reference(s) |
T85CC2 | Peptidyl-prolyl cis-trans isomerase D | PPID |
Q08752 |
1 Reference(s) |
T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
2 Reference(s) |
T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
T02JCT | Protein AATF | AATF |
Q9NY61 |
1 Reference(s) |
T08J6P | NA | MIR146B |
NA |
1 Reference(s) |
T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
T90ORW | Bcl2-associated agonist of cell death | BAD |
Q92934 |
1 Reference(s) |
T89GCM | Inward rectifier potassium channel 2 | KCNJ2 |
P63252 |
1 Reference(s) |
T90XYZ | C-reactive protein | CRP |
P02741 |
1 Reference(s) |
T43Y5O | D(3) dopamine receptor | DRD3 |
P35462 |
1 Reference(s) |
T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
1 Reference(s) |
T68WYW | von Willebrand factor | VWF |
P04275 |
1 Reference(s) |
T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
2 Reference(s) |
T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
1 Reference(s) |
T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
1 Reference(s) |
T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
1 Reference(s) |
T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |