Compound Description
| ID: C0190 | Common name: Linolenic Acid |
| IUPAC: (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid | CAS: CAS:463-40-1 |
| Chembl ID: CHEMBL8739 | Pubchem ID: CID:5280934 |
| Formula: C18H30O2 | TCM-ID: TCMC1496 |
| Smiles: CCC=CCC=CCC=CCCCCCCCC(=O)O | |
| Alias:
9,12,15-Octadecatrienoic acid, (Z,Z,Z)-;
Linolenic acid; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid; (Z,Z,Z)-Octadeca-9,12,15-trienoic acid; (all-Z)-9,12,15-Octadecatrienoic acid |
Structure:
|
Related Targets (Total: 9)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
| T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
B | 1 Reference(s) |
| T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG |
P01275 |
B | 1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
B | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
B | 1 Reference(s) |
| T70HC9 | Hepatocyte nuclear factor 1-alpha | HNF1A |
P20823 |
C | 1 Reference(s) |
| T49J7I | Hepatocyte nuclear factor 4-alpha | HNF4A |
P41235 |
C | 1 Reference(s) |
| T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 |
P55851 |
C | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 132)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0743 | Yi Zhi Ren | 益智仁 | Sharpleaf galangal | Alpinia oxyphylla |
| H0713 | Che Qian Cao | 车前草 | all-grass of rippleseed plantain | Plantago depressa |
| H0308 | Pi Ba Ren | 枇杷仁 | NA | Eriobotrya japonica |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0332 | Qiao Mai | 荞麦 | Common buckwheat | Fagopyrum esculentum |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0238 | Mei Hua | 梅花 | Plum flower | Flos mume |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0239 | Bei Sha Shen | 北沙参 | Coastal glehnia | Glehnia littoralis |
| H0878 | Ba Dou Shuang | 巴豆霜 | Defatted croton seed powder | Croton tiglium |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0584 | Tu Wu Jia | 土五加 | NA | Acanthopanax gracilistylus |
| H0585 | Tu Yin Chen Hao | 土茵陈蒿 | Capillary wormwood | Artemisia capillaris |
| H0597 | Wu Jia Pi | 五加皮 | Slenderstyle acanthopanax root-bark | Acanthopanax gracilistylus |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H0126 | Lai Fu Zi | 莱菔子 | Garden radish seed | Raphanus sativus |
| H0242 | Bei Sha Shen Liu Jin Gao | 北沙参流浸膏 | Glehnia littoralis | Glehnia littoralis |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0255 | Mao Zhao Cao | 猫爪草 | Root of catclaw buttercup | Ranunculus ternatus |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H1107 | Gua Lou Ren Shuang | 瓜蒌仁霜 | NA | Trichosanthes kirilowii |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0558 | Ting Li Zi | 葶苈子 | Descurainia sophia | Lepidium apetalum |
| H0746 | Yin Chen Hao Gan Jin Gao | 茵陈蒿干浸膏 | Capillary wormwood | Artemisia capillaris |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H1244 | Huang Miao | 黄苗 | NA | Taraxacum mongolicum |
| H0998 | Dong Gua Pi | 冬瓜皮 | Chinese waxgourd peel | Benincasa hispida |
| H0028 | Jiang Huang | 姜黄 | Common turmeric | Curcuma longa |
| H0380 | San Qi Gan Jin Gao | 三七干浸膏 | Sanchi | Panax notoginseng |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H0418 | Shan Yin Chen | 山茵陈 | Capillary wormwood | Artemisia capillaris |
| H0466 | Cai Fu Zi | 菜菔子 | Semen raphani | Raphanus sativus |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H1105 | Gua Lou Pi | 瓜蒌皮 | NA | Trichosanthes kirilowii |
| H0969 | Di Fu Zi | 地肤子 | fruit of belvedere | Fructus kochiae |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
| H0604 | Wu Wei Teng | 五味藤 | NA | Securidaca inappendiculata |
| H0850 | Zi Su Ye | 紫苏叶 | Common perilla leaf | Perilla frutescens var. arguta |
| H0535 | Teng Wu Jia Gen | 藤五加根 | NA | Acanthopanax gracilistylus |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H1176 | Hei Hu Jiao | 黑胡椒 | Black pepper | Piper nigrum |
| H0384 | San Qi Ye | 三七叶 | Folium panax notoginseng | Panax notoginseng |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H1171 | He Zi Rou | 诃子肉 | Medicine terminalia | Terminalia chebula |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H0484 | Shui Fei Ji | 水飞蓟 | St marys | Silybum marianum |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
| H0688 | Xuan Shen | 玄参 | Ningpo figwort | Scrophularia ningpoensis |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H1077 | Bai Hu Jiao | 白胡椒 | white pepper | Piper nigrum |
| H0614 | Wu Zhao Long | 五爪龙 | Cairo morningglory | Ipomoea cairica |
| H1170 | He Zi | 诃子 | Medicine terminalia | Terminalia chebula |
| H0895 | Chuan Yu Jin | 川郁金 | Turmeric | Curcuma longa |
| H0573 | Tu Jia Pi | 土加皮 | NA | Acanthopanax gracilistylus |
| H0094 | Gou Qi | 枸杞 | Chinese wolfberry fruit | Lycium chinense |
| H0715 | Che Qian Zi | 车前子 | seed of asiatic pantain | Plantago asiatica |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0849 | Zi Su Geng | 紫苏梗 | Common perilla stem | Perilla frutescens var. arguta |
| H0385 | San Qi Ye Jing | 三七叶茎 | Sanchi | Panax notoginseng |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H0745 | Yin Chen Hao | 茵陈蒿 | Capillary wormwood | Artemisia capillaris |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H1204 | Hu Jiao | 胡椒 | Black pepper | Piper nigrum |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0729 | Ye Ju Hua | 野菊花 | Indian wild chrysanthemum flower | Chrysanthemum indicum |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0409 | Shan Jiang | 山姜 | shell ginger | Alpinia zerumbet |
| H1106 | Gua Lou Ren | 瓜蒌仁 | NA | Trichosanthes kirilowii |
| H0768 | Yuan Shen | 元参 | Figwort root | Scrophularia ningpoensis |
| H0314 | Pu Gong Ying | 蒲公英 | Mongolian dandelion | Taraxacum mongolicum |
| H0315 | Pu Gong Ying Jin Gao | 蒲公英浸膏 | Mongolian dandelion | Taraxacum mongolicum |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0869 | Ba Dou | 巴豆 | Pu rging croton | Croton tiglium |
| H0095 | Gou Qi Zi | 枸杞子 | Chinese wolfberry fruit | Lycium chinense |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0697 | Ya Ma Zi | 亚麻子 | Common flax seed | Linum usitatissimum |
| H1232 | Huang Cao Wu | 黄草乌 | NA | Aconitum vilmorinianum |
| H0888 | Ba Dou Ye | 巴豆叶 | Pu rging croton | Croton tiglium |
| H1000 | Dong Gua Zi | 冬瓜子 | Chinese waxgourd seed | Benincasa hispida |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H0382 | San Qi Hua | 三七花 | Sanchi | Panax notoginseng |
| H0383 | San Qi Jing Ye | 三七茎叶 | Sanchi | Panax notoginseng |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0381 | San Qi Gao Fen | 三七膏粉 | Sanchi | Panax notoginseng |
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0740 | Yi Zhi | 益智 | Fructus alpinae oxyphyllae | Alpinia oxyphylla |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0073 | Jing Jie Sui | 荆芥穗 | NA | Schizonepetae spica |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1110 | Gua Lou Zi | 瓜蒌子 | mongolian snakegourd seed | Trichosanthes kirilowii maxim |
| H0003 | Huo Ma Ren | 火麻仁 | Hemp fimble seed | Cannabis sativa |
| H1112 | Gua Lou Ren(1) | 栝楼仁 | NA | Trichosanthes kirilowii |
| H1104 | Gua Lou | 瓜蒌 | NA | Trichosanthes kirilowii |
| H0249 | Bei Ting Li Zi | 北葶苈子 | Descurainia sophia | Lepidium apetalum |
| H0125 | Lai Fu | 莱菔 | Garden radish | Raphanus sativus |
| H0679 | Xing Ren | 杏仁 | Apricot seed | Prunus armeniaca |
| H1111 | Gua Lou Gen | 栝楼根 | NA | Trichosanthes kirilowii |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H1011 | Bai Chou | 白丑 | Pharbitis seed | Semen pharbitidis |
| H1108 | Gua Lou Shi | 栝蒌实 | NA | Trichosanthes kirilowii |
| H0557 | Ting Li Cao | 葶苈草 | Descurainia sophia | Lepidium apetalum |
| H0547 | Cang Qing Guo | 藏青果 | Myrobalan | Terminalia chebula |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H1173 | Hei Chou | 黑丑 | Pharbitis seed | Semen pharbitidis |
| H0539 | Tian Hua Fen | 天花粉 | Mongolian snakegourd root | Trichosanthes kirilowii |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0204 | Ma Ren | 麻仁 | NA | Cannabis sativa |
Ckey description of the interaction between compound and target